CD10 (MME) Mouse Monoclonal Antibody [Clone ID: 2A1H5E1]
Product Data | |
Clone Name | 2A1H5E1 |
---|---|
Application | IHC |
Recommended Dilution | ELISA: 1/10000. Immunohistochemistry on Paraffin Sections: 1/200 - 1/1000. |
Reactivity | Human |
Antibody Host | Mouse |
Isotype | IgG2b |
Clonality | Monoclonal |
Immunogen | Purified recombinant fragment of Human CD-10 expressed in E. Coli. |
Specificity | Recognizes CD10 |
Buffer | PBS State: Purified State: Liquid purified IgG fraction Preservative: 0.03% Sodium Azide |
Conjugation | Unconjugated |
Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. |
Stability | Shelf life: one year from despatch. |
Shipping | Blue Ice |
Gene Name | membrane metallo-endopeptidase |
Database Link | |
Background | CD10 is a 100kDa glycoprotein, also designated Common Acute Lymphocytic Leukemia Antigen (CALLA). It is a cell surface enzyme with neutral metalloendopeptidase activity which inactivates a variety of biologically active peptides. CD10 is expressed on the cells of lymphoblastic, Burkitt’s, and follicular germinal center lymphomas, and on cells from patients with chronic myelocytic leukemia (CML). It is also expressed on the surface of normal early lymphoid progenitor cells, immature B cells within adult bone marrow and germinal center B cells within lymphoid tissue. CD10 is also present on breast myoepithelial cells, bile canaliculi, fibroblasts, with especially high expression on the brush border of kidney and gut epithelial cells. |
Synonyms | MME, EPN, Neutral endopeptidase 24.11, Neutral endopeptidase, NEP, Enkephalinase, Atriopeptidase, CALLA |
Reference Data |
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