Rituximab Rat Monoclonal Antibody [Clone ID: MB2 A4]

CAT#: AM05879HR-N

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Rituximab rat monoclonal antibody, clone MB2 A4, HRP, Purified


 Product Datasheet for 'AM05879HR-N'

  View other "MB2 A4" antibodies (2)

USD 900.00


Availability*
5 Days

Size
    • 100 ug


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Specifications

Product Data
Clone Name MB2 A4
Applications ELISA
Recommend Dilution ELISA: 1/20000-1/20000.
Host Rat
Isotype IgG2a
Clonality Monoclonal
Immunogen F(ab)2 fragment of Rituximab
Specificity This antibody specifically recognises the idiotypic determinants expressed by the Rituximab humanised monoclonal antibody. 
This antibody does not recognise other CD20 antibodies.
It has been used to detect Rituximab bound to the surface of the Raji B cell line, however detection of Rituximab bound 'in vivo' to B-CLL cells has not been demonstrated. It is possible that complement deposition on Rituximab opsonised cells inhibits binding of the anti-Rituximab antibody to cell bound Rituximab (3).
Clone MB2A4 has been used in ELISA assays to monitor the levels of rituximab in patient serum following therapy (4,5).
Formulation PBS
Label: HRP
State: Purified
State: Liquid purified IgG fraction from Tissue Culture Supernatant
Stabilizer: HRP stabilizer (containg no Azide, no Mercury, no BSA or other Bovine material, but weak concentrations of Rabbit antibodies).
Preservative: 0.01% Thiomersal
Concentration 1.0 mg/ml
Purification Affinity chromatography on Protein G
Conjugation HRP
Background Rituximab is a therapeutic reagent directed against the human CD20 cell surface antigen.
Synonyms Rituxan, MabThera
Reference Data

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