CD272 (BTLA) Mouse Monoclonal Antibody [Clone ID: MIH26]

CAT#: AM05617PU-N

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CD272 (BTLA) mouse monoclonal antibody, clone MIH26, Purified

 Product Datasheet for 'AM05617PU-N'

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USD 330.00

5 Days

    • 100 ug

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Product Data
Clone Name MIH26
Applications FC, IHC
Recommend Dilution Flow Cytometry: Use 10 µl of 1/10-1/200 diluted antibody to label 1x106 cells in 100 µl. 
Immunohistochemistry on Frozen Sections.
Histology Positive Control Tissue: Human tonsil.
Reactivity Human
Host Mouse
Isotype IgG2a
Clonality Monoclonal
Immunogen BTLA - transfected L cells
Specificity This antibody detects CD272, also known as B- and T-lymphocyte attenuator (BTLA).
Formulation PBS, pH 7.4
State: Purified
State: Liquid purified IgG fraction
Preservative: 0.09% Sodium Azide
Concentration 1.0 mg/ml
Purification Affinity Chromatography on Protein G
Background CD272 is a type I transmembrane glycoprotein which is structurally and functionally related to cytotoxic T lymphocyte antigen-4 (CTLA-4), and programmed death-1 (PD-1). CD272 is a T-cell inhibitory receptor that regulates T cell activation through its interaction with herpes virus entry mediator (HVEM), a co-stimulator receptor of the TNFR family.
CD272 may negatively regulate T-cell dependent autoimmune reaction, and polymorphisms in its gene have been associated with Rheumatoid Arthritis.
Synonyms BTLA1; CD272; FLJ16065; MGC129743
Reference Data

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