alpha Synuclein (SNCA) Mouse Monoclonal Antibody [Clone ID: 4D6]
| Product Data | |
| Clone Name | 4D6 |
|---|---|
| Application | ELISA, IHC, WB |
| Recommended Dilution | ELISA. Western/Dot Blot: 1/100-1/10,000. Immunohistochemistry on Frozen and Formalin-Fixed Paraffin Embedded Tissues: 1/100-1/1000 (No formic Acid, Enzyme or HIER required). |
| Reactivity | Human |
| Antibody Host | Mouse |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Immunogen | Purified E. coli produced Human Alpha-Synuclein. |
| Specificity | This antibody recognizes Human Alpha-Synuclein. Other species not tested. |
| Buffer | PBS State: Purified State: Liquid purified Ig fraction from Tissue Culture Supernatant Preservative: None |
| Concentration | lot specific |
| Purification | Protein A Chromatography |
| Conjugation | Unconjugated |
| Storage | Upon receipt, store undiluted (in aliquots) at -20°C. Avoid repeated freezing and thawing. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Gene Name | synuclein alpha |
| Database Link | |
| Background | Synuclein-alpha is the major component of Lewy bodies and Lewy neuritis in sporadic PD. dementia with Lewy Bodies and Lewy Body variant of AD. Lewy bodies are composed of truncated and phosphorylated intermediate neurofilament proteins, alpha synuclein, ubiquitin and associated enzymes. The synuclein phosphoproteins (15-20kDa) are small highly conserved proteins in vertebrates. The synuclein family includes alpha and beta synucleins and loosely related gamma-synuclein and synoretin. The expression is abundant in neurons and typically localized at presynaptic terminals. |
| Synonyms | NACP, PARK1 |
| Reference Data | |
Write Your Own Review
| Product Manuals |
| FAQs |
| SDS |
Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.