CD24 Mouse Monoclonal Antibody [Clone ID: SN3]
$1,000.00
5 Days*
Specifications
| Product Data | |
| Clone Name | SN3 |
|---|---|
| Application | FC, IHC |
| Recommended Dilution | Immunohistochemistry on frozen sections. Flow Cytometry. |
| Reactivity | Human |
| Antibody Host | Mouse |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Immunogen | Glycoproteins purified from human NALM-1 cell line |
| Specificity | This antibody recognises the CD24 cell surface antigen, a heavily glycosylated molecule of 35-45kD, expressed by granulocytes and B lymphocytes, and by some activated T cells and T cell malignancies. |
| Buffer | Phosphate buffered saline pH7.4 State: Low Endotoxin State: Liquid purified IgG |
| Concentration | lot specific |
| Purification | Affinity chromatography on Protein G |
| Conjugation | Unconjugated |
| Storage | Store the antibody at -20°C. Avoid repeated freezing and thawing. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Gene Name | CD24 molecule |
| Database Link | |
| Background | CD24 (also known as heat stable antigen) is a phosphatidylinositol linked cell surface glycoprotein with a polypeptide core of 30 amino acids and high carbohydrate content. The apparent molecular mass of the two forms of CD24 purified from a mouse lymphoma cell line appear to be in the range of 40-60 and 23-30 kDa. CD24 is expressed at all stages of B cell development and on most thymocytes. The absence of expression from mature T cells is closely associated with their maturation from CD4+ CD8+ CD24+ thymocytes to either CD4+ CD8- CD24- or CD4- CD8+ CD24- T cells. CD24 is also present on mouse granulocytes, monocytes, Langerhans cells and erythrocytes. Its ligand is P selectin (CD62P). CD24 may play a role in regulation of B cell proliferation and differentiation, and it has been proposed that heat stable antigen promotes homotypic adhesion between B lymphocytes. CD24 is also a positive marker of pancreatic cancer. |
| Synonyms | X62 heat stable antigen, HSA |
| Note | Endotoxin Level: <0.01EU/µg |
| Reference Data | |
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.