BNP (NPPB) (NT-proBNP 1-21) Mouse Monoclonal Antibody [Clone ID: 21-6-6]

SKU AM02178PU-S

BNP (NPPB) (NT-proBNP 1-21) mouse monoclonal antibody, clone 21-6-6, Purified

Product Data

• Clone Name: 21-6-6
• Application: ELISA, IHC
• Recommended Dilution: ELISA.; Immunohistochemistry Paraffin Sections: 1/25 (Ref.1).
• Reactivity: Human
• Antibody Host: Mouse
• Isotype: IgG2a
• Clonality: Monoclonal
• Immunogen: Synthetic Human pro-BNP (aa 1-21) poly-Lysine conjugated
• Specificity: This antibody detects Synthetic Human proBNP (aa 1-21), Human proBNP
• Buffer: 200 mM Sodium Citrat / Tris, 500 mM NaCl buffer pH 7.5 containing 0.02% Sodium Azide; State: Purified; State: Lyophilized purified Cell Culture Supernatant
• Reconstitution Method: Restore in aqua bidest to 1 mg/ml
• Purification: Protein A Chromatography
• Conjugation: Unconjugated
• Storage: Store lyophilized at 2-8°C and reconstituted at -20°C.; Avoid repeated freezing and thawing.
• Stability: Shelf life: One year from despatch.
• Shipping: Ambient
• Gene Name: natriuretic peptide B
• Database Link:
  P16860
• Background: In cardiac tissue brain natriuretic peptide (BNP) is synthesized as 134 amino acid precursor (prepro-BNP), which is cleaved by proteases to form a 26 aa "signal" peptide and a 108 aa pro-BNP. Proteolytic digestion of pro-BNP results in formation of 76 aa amino-terminal NT-proBNP and biologically active 32 aa BNP hormone molecule. Both proBNP and NTproBNP circulate in human plasma and have been proposed as markers for early diagnosis of left ventricular dysfunction as well as prognostic markers of possible cardiac complications at patients with heart failure.
• Synonyms: NPPB, Brain natriuretic peptide, BNP, proBNP
• Note: LocusID 4879

Reference Data