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Complement factor B (CFB) (Bb Fragment) Mouse Monoclonal Antibody [Clone ID: 10-09]

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SKU
AM01333PU-N
Complement factor B (CFB) (Bb Fragment) mouse monoclonal antibody, clone 10-09, Purified
Size:
100 ug
Conjugation:
Unconjugated
  $845.00
5 Days*
Size
Bulk/Customize

View other "Complement factor B or NP_001701" antibodies

Specifications
Specifications
Product Data
Clone Name 10-09
Application ELISA, FC, IHC, WB
Recommended Dilution ELISA: This antibody binds to both the Bb fragment and complement factor B so is not suitable for all ELISA applications.
Western Blot.
Flow Cytometry.
Immunohistochemistry on frozen sections.
Recommended Positive Control: Kidney from post streptocial glomerlulonephritis patients.
Reactivity Human
Antibody Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Human factor B
Specificity This antibody recognises the Bb fragment of 90 kDa complement factor B, present in blood serum.
Buffer Borate buffered saline containing 0.09% Sodium Azide
State: Purified
State: Liquid purified Ig
Concentration lot specific
Purification Affinity chromatography on Protein A
Conjugation Unconjugated
Storage Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Shipping Blue Ice
Gene Name complement factor B
Database Link
Background C3b associates with complement factor B, inducing conformational change which enables complement factor D to cleave the N-terminal of complement factor B, the Ba subunit, leaving the 63 kDa Bb subunit associated with C3b and forming C3 convertase. Subunit Bb is involved in the proliferation of preactivated B lymphocytes. Conversely, Ba inhibits lymphocyte proliferation.
Synonyms Properdin factor B, C3/C5 convertase, PBF2, CFB, BF, BFD
Reference Data
Protein Families Druggable Genome, Protease, Secreted Protein
Protein Pathways Complement and coagulation cascades
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.