Resources for CD 19 | Biomarker for normal and neplastic B cell

CD19 is a biomarker for B cell lineage and positively regulates mature B cell antigen receptor signal transduction cascade. CD19 has been used to diagnose diseases related to B-Cell Lymphomas, including Non-Hodgkin lymphomas (NHL), acute lymphoblastic leukemia (ALL), and chronic lymphocytic leukemia (CLL). CD19 monoclonal antibody is widely studied for therapies of lymphoma, leukemia and autoimmune disorders, especially in the clinical trials of chimeric antigen receptor (CAR) T-cell therapy.

car expressing t-cell

A schematic of an anti-CD19 CAR-expressing T-cell recognizing a CD19+ malignant cell. CAR, chimeric antigen receptor

CD19 UltraMab™ Antibody

SKU# UM500071 (100ul) & UM570071 (30ul)
Clone Name UMAB103
Target Homo sapiens CD19 molecule (CD19), transcript variant 2
Host Mouse
Reactivity Human
Tested Application WB, IHC, FC
Dilution WB: 1:500, IHC: 1:200, FC: 1:50
ihc-staining of FFPE human B-cell Lymphoma using Anti-CD19

IHC staining of FFPE human B-Cell Lymphoma using anti-CD19 mouse monoclonal antibody (SKU# UM500071; heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120oC for 3min).

flow-cytometric-analysis of viable B-cell Lymphoma

Flow cytometric analysis of viable B-Cell Lymphoma cell line (Raji) using anti-CD19 antibody at 1:20 (UM500071, red), compared to isotype control (anti-DDK TA180144, green), and negative control (PBS, blue).

Protein Name Antibody Description SKU
CD20 Purified CD20 (MS4A1) mouse monoclonal antibody,clone UMAB58 UM800009
CD21 Rabbit Polyclonal Anti-CR2 (CD21) Antibody TA350811
CD22 CD22 mouse monoclonal antibody, clone OTI4C3 TA506412
CD22 CD22 mouse monoclonal antibody, clone OTI4C3 TA506412
CD24 Mouse Anti-Human CD24 Purified, Clone eBioSN3 (SN3 A5-2H10) TA320249
CD25 Anti-IL2RA (CD25) Rabbit Polyclonal Antibody TA323669
CD27 Mouse Anti-Human CD27 Purified, Clone O323 TA320253
CD38 CD38 mouse monoclonal antibody,clone OTI1C9 TA804538
CD3E CD3E mouse monoclonal antibody,clone UMAB54 UM500048
CD45R/B220 PTPRC (CD45R) mouse monoclonal antibody, clone OTI1B7 TA506054
CD69 Anti-CD69 Rabbit Polyclonal Antibody TA321397
CD81 Rabbit Polyclonal CD81 Antibody TA306789
CD81 Rabbit Polyclonal CD81 Antibody TA306789
CD82 Rabbit Polyclonal KAI1 (CD82) Antibody TA306407
CR2 Rabbit Polyclonal Anti-CR2 Antibody TA350811
IFN-r Rabbit polyclonal anti-IFN alpha 2b (IFN-R) antibody TA319105
IL-10 ELISA and Luminex validated biotinylated lL-10 Rat monoclonal antibody, clone OTI12G8 TA700017
IL-2 Rabbit polyclonal IL-2 antibody Peroxidase Conjugated TA319284
IL-6 IL6 mouse monoclonal antibody, clone OTI3G9 TA500067
Lyn Rabbit Polyclonal Anti-LYN Antibody TA350146
SHP-1 Rabbit polyclonal SHP-1 (Ab-564) antibody TA312507
TNF-a TNF mouse monoclonal antibody, clone OTI1C1 TA506513
VAV2 Rabbit Polyclonal Anti-VAV2 Antibody TA351911