Gene editing with CRISPR-CAS9 kits

What is CRISPR CAS9?

CRISPR/Cas9, is an RNA-guided targeted genome editing tool which allows researchers to do gene knockout, knockin SNPs, insertions and deletions in cell lines and animals. The CRISPR/Cas9 genome editing system requires two components: Cas9, the endonuclease, and a guide RNA (sgRNA) which guides Cas9 to a specific location in the genome sequence. With the protospacer-adjacent motif (PAM - the sequence NGG) present at the 3′ end, Cas9 will unwind the DNA duplex and cleave both strands upon recognition of a target sequence by the guide RNA.

Products and Services

OriGene provides reagents to support a broad range of CRISPR/Cas9 gene editing applications. Click the following gene editing related product below and learn more about how we can help you.

This award recognizes OriGene as having the best Bioz Star scores in the CRISPR category among 50,000+ suppliers. Learn more.

CRISPR Resources


Recent Citations using our CRISPR products

1. GBA Regulates EMT/MET and Chemoresistance in Squamous Cell Carcinoma Cells by Modulating the Cellular Glycosphingolipid Profile

Published in Cells, 2023 Jul, using KN201614BN
PubMed: 37508550

2. Regulation of microRNA expression by the adaptor protein GRB2

Published in Scientific Reports, 2023 Jun, using KN200469
PubMed: 37328606

3. Development of a Novel σ 1 Receptor Biosensor Based on Its Heterodimerization with Binding Immunoglobulin Protein in Living Cells.

Published in ACS chemical neuroscience, 2023 Jun, using KN201206
PubMed: 37191585

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