Tbl1xr1 Mouse shRNA Plasmid (Locus ID 81004)

SKU TR511773

Tbl1xr1 - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector, 5µg of each construct provided

Product Data

• Locus ID: 81004
• Synonyms: 8030499H02Rik; A630076E03Rik; AW539987; C21; C230089I12Rik; DC42; Ira1; TBLR1
• Vector: pRS
• E. coli Selection: Ampicillin
• Format: Retroviral plasmids
• Components: Tbl1xr1 - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 81004). 5µg purified plasmid DNA per construct; 29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free.
• RefSeq: NM_030732, NM_030732.1, NM_030732.2, NM_030732.3, BC018512, BC141541
• UniProt ID: Q8BHJ5
• Summary: F-box-like protein involved in the recruitment of the ubiquitin/19S proteasome complex to nuclear receptor-regulated transcription units. Plays an essential role in transcription activation mediated by nuclear receptors. Probably acts as integral component of the N-Cor corepressor complex that mediates the recruitment of the 19S proteasome complex, leading to the subsequent proteasomal degradation of N-Cor complex, thereby allowing cofactor exchange, and transcription activation (By similarity).[UniProtKB/Swiss-Prot Function]
• shRNA Design: These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
• Shipping: Ambient