Lpin1 Mouse shRNA Plasmid (Locus ID 14245)

SKU TR500718

Lpin1 - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector, 5µg of each construct provided

Product Data

• Locus ID: 14245
• Synonyms: 4631420P06; fld; Kiaa0188; Lipin1; mKIAA0188
• Vector: pRS
• E. coli Selection: Ampicillin
• Format: Retroviral plasmids
• Components: Lpin1 - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 14245). 5µg purified plasmid DNA per construct; 29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free.
• RefSeq: BC042462, NM_001130412, NM_015763, NM_172950, NM_001355598, NM_015763.1, NM_015763.2, NM_015763.3, NM_015763.4, NM_001130412.1, NM_172950.1, NM_172950.2, NM_172950.3
• UniProt ID: Q91ZP3
• Summary: Plays important roles in controlling the metabolism of fatty acids at different levels. Acts as a magnesium-dependent phosphatidate phosphatase enzyme which catalyzes the conversion of phosphatidic acid to diacylglycerol during triglyceride, phosphatidylcholine and phosphatidylethanolamine biosynthesis. Acts also as nuclear transcriptional coactivator for PPARGC1A/PPARA regulatory pathway to modulate lipid metabolism gene expression. Is involved in adipocyte differentiation. Isoform 1 is recruited at the mitochondrion outer membrane and is involved in mitochondrial fission by converting phosphatidic acid to diacylglycerol.[UniProtKB/Swiss-Prot Function]
• shRNA Design: These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
• Shipping: Ambient