LOX Human shRNA Plasmid Kit (Locus ID 4015)

SKU TR316606

LOX - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector, 5µg of each construct provided

Product Data

• Locus ID: 4015
• Synonyms: AAT10
• Vector: pRS
• E. coli Selection: Ampicillin
• Format: Retroviral plasmids
• Components: LOX - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 4015). 5µg purified plasmid DNA per construct; 29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free.
• RefSeq: NM_001178102, NM_001317073, NM_002317, NM_002317.1, NM_002317.2, NM_002317.3, NM_002317.4, NM_002317.5, NM_002317.6, NM_001178102.1, NM_001178102.2, BC074820, BC074872, BC089436, NM_002317.7
• UniProt ID: P28300
• Summary: This gene encodes a member of the lysyl oxidase family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate a regulatory propeptide and the mature enzyme. The copper-dependent amine oxidase activity of this enzyme functions in the crosslinking of collagens and elastin, while the propeptide may play a role in tumor suppression. In addition, defects in this gene have been linked with predisposition to thoracic aortic aneurysms and dissections. [provided by RefSeq, Jul 2016]
• shRNA Design: These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
• Shipping: Ambient