DHLAG (CD74) Human shRNA Plasmid Kit (Locus ID 972)

SKU TR314068

CD74 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector, 5µg of each construct provided

Product Data

• Locus ID: 972
• Synonyms: DHLAG; HLADG; Ia-GAMMA; II; p33
• Vector: pRS
• E. coli Selection: Ampicillin
• Format: Retroviral plasmids
• Components: CD74 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 972). 5µg purified plasmid DNA per construct; 29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free.
• RefSeq: NM_001025158, NM_001025159, NM_004355, NM_004355.1, NM_004355.2, NM_004355.3, NM_001025158.1, NM_001025158.2, NM_001025159.1, NM_001025159.2, BC018726, BC018726.1, BC024272, NR_157074, NM_001364083, NM_001364084
• UniProt ID: P04233
• Summary: The protein encoded by this gene associates with class II major histocompatibility complex (MHC) and is an important chaperone that regulates antigen presentation for immune response. It also serves as cell surface receptor for the cytokine macrophage migration inhibitory factor (MIF) which, when bound to the encoded protein, initiates survival pathways and cell proliferation. This protein also interacts with amyloid precursor protein (APP) and suppresses the production of amyloid beta (Abeta). Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2011]
• shRNA Design: These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
• Shipping: Ambient