p95 NBS1 (NBN) Human shRNA Plasmid Kit (Locus ID 4683)

SKU TR311260

NBN - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector, 5µg of each construct provided

Product Data

• Locus ID: 4683
• Synonyms: AT-V1; AT-V2; ATV; NBS; NBS1; P95
• Vector: pRS
• E. coli Selection: Ampicillin
• Format: Retroviral plasmids
• Components: NBN - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 4683). 5µg purified plasmid DNA per construct; 29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free.
• RefSeq: NM_001024688, NM_002485, NM_002485.2, NM_002485.3, NM_002485.4, NM_001024688.1, BC005293, BC016762, BC040519, BC071590, BC108650, BC136802, BC136803, BC143065, BC143066, BC144413, BC146797, NM_002485.5
• UniProt ID: O60934
• Summary: Mutations in this gene are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. The encoded protein is a member of the MRE11/RAD50 double-strand break repair complex which consists of 5 proteins. This gene product is thought to be involved in DNA double-strand break repair and DNA damage-induced checkpoint activation. [provided by RefSeq, Jul 2008]
• shRNA Design: These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
• Shipping: Ambient