epithelial Sodium Channel alpha (SCNN1A) Human shRNA Plasmid Kit (Locus ID 6337)

SKU TR309608

SCNN1A - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector, 5µg of each construct provided

Product Data

• Locus ID: 6337
• Synonyms: BESC2; ENaCa; ENaCalpha; LIDLS3; SCNEA; SCNN1
• Vector: pRS
• E. coli Selection: Ampicillin
• Format: Retroviral plasmids
• Components: SCNN1A - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 6337). 5µg purified plasmid DNA per construct; 29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free.
• RefSeq: NM_001038, NM_001159575, NM_001159576, NM_001038.1, NM_001038.2, NM_001038.3, NM_001038.4, NM_001038.5, NM_001159575.1, NM_001159576.1, BC062613, BC062613.1, BC006526, BC037417, NM_001159576.2, NM_001038.6
• UniProt ID: P37088
• Summary: Nonvoltage-gated, amiloride-sensitive, sodium channels control fluid and electrolyte transport across epithelia in many organs. These channels are heteromeric complexes consisting of 3 subunits: alpha, beta, and gamma. This gene encodes the alpha subunit, and mutations in this gene have been associated with pseudohypoaldosteronism type 1 (PHA1), a rare salt wasting disease resulting from target organ unresponsiveness to mineralocorticoids. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Apr 2009]
• shRNA Design: These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
• Shipping: Ambient