Acid sphingomyelinase (SMPD1) Human shRNA Plasmid Kit (Locus ID 6609)

SKU TR309232

SMPD1 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector, 5µg of each construct provided

Product Data

• Locus ID: 6609
• Synonyms: ASM; ASMASE; NPD
• Vector: pRS
• E. coli Selection: Ampicillin
• Format: Retroviral plasmids
• Components: SMPD1 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 6609). 5µg purified plasmid DNA per construct; 29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free.
• RefSeq: NM_000543, NM_001007593, NM_001318087, NM_001318088, NR_027400, NR_134502, NM_000543.1, NM_000543.2, NM_000543.3, NM_000543.4, NM_001007593.1, NM_001007593.2, BC041164, BM686561, BM977655, NM_001365135, NM_001007593.3, NM_000543.5
• UniProt ID: P17405
• Summary: The protein encoded by this gene is a lysosomal acid sphingomyelinase that converts sphingomyelin to ceramide. The encoded protein also has phospholipase C activity. Defects in this gene are a cause of Niemann-Pick disease type A (NPA) and Niemann-Pick disease type B (NPB). Multiple transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2010]
• shRNA Design: These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
• Shipping: Ambient