PUF60 Human shRNA Plasmid Kit (Locus ID 22827)

SKU TR307443

PUF60 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector, 5µg of each construct provided

Product Data

• Locus ID: 22827
• Synonyms: FIR; RoBPI; SIAHBP1; VRJS
• Vector: pRS
• E. coli Selection: Ampicillin
• Format: Retroviral plasmids
• Components: PUF60 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 22827). 5µg purified plasmid DNA per construct; 29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free.
• RefSeq: BC009734, BC011265, NM_001136033, NM_001271096, NM_001271097, NM_001271098, NM_001271099, NM_001271100, NM_014281, NM_078480, NM_014281.1, NM_014281.2, NM_014281.3, NM_014281.4, NM_078480.1, NM_078480.2, NM_001136033.1, NM_001136033.2, NM_001271100.1, NM_001271097.1, NM_001271099.1, NM_001271096.1, NM_001271098.1, BC009734.1, BC011265.1, BC008875, BC011979, BC035435, NM_001362895, NM_001362897, NM_001362896, NM_001271100.2, NM_001271097.2, NM_001271099.2, NM_001271096.2, NM_001136033.3, NM_014281.5, NM_001271098.2, NM_078480.3
• UniProt ID: Q9UHX1
• Summary: This gene encodes a nucleic acid-binding protein that plays a role in a variety of nuclear processes, including pre-mRNA splicing and transcriptional regulation. The encoded protein forms a complex with the far upstream DNA element (FUSE) and FUSE-binding protein at the myelocytomatosis oncogene (MYC) promoter. This complex represses MYC transcription through the core-TFIIH basal transcription factor. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2012]
• shRNA Design: These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
• Shipping: Ambient