CTAG2 Human shRNA Plasmid Kit (Locus ID 30848)

SKU TR305187

CTAG2 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector, 5µg of each construct provided

Product Data

• Locus ID: 30848
• Synonyms: CAMEL; CT2; CT6.2; CT6.2a; CT6.2b; ESO2; LAGE-1; LAGE2B
• Vector: pRS
• E. coli Selection: Ampicillin
• Format: Retroviral plasmids
• Components: CTAG2 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 30848). 5µg purified plasmid DNA per construct; 29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free.
• RefSeq: NM_020994, NM_172377, NM_020994.1, NM_020994.2, NM_020994.3, NM_020994.4, NM_172377.1, NM_172377.2, NM_172377.3, NM_172377.4, BC002833, BC002833.2, BC113998, BC114933, BC128045, NM_020994.5
• UniProt ID: O75638
• Summary: This gene encodes an autoimmunogenic tumor antigen that belongs to the ESO/LAGE family of cancer-testis antigens. This protein is expressed in a wide array of cancers including melanoma, breast cancer, bladder cancer and prostate cancer. This protein is also expressed in normal testis tissue. An alternative open reading frame product of this gene has been described in PMID:10399963. This alternate protein, termed CAMEL, is a tumor antigen that is recognized by melanoma-specific cytotoxic T-lymphocytes. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]
• shRNA Design: These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
• Shipping: Ambient