Lipin 1 (LPIN1) Human shRNA Plasmid Kit (Locus ID 23175)

SKU TR303494

LPIN1 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector, 5µg of each construct provided

Product Data

• Locus ID: 23175
• Synonyms: PAP1
• Vector: pRS
• E. coli Selection: Ampicillin
• Format: Retroviral plasmids
• Components: LPIN1 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 23175). 5µg purified plasmid DNA per construct; 29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free.
• RefSeq: NM_001261427, NM_001261428, NM_001261429, NM_145693, NM_001349199, NM_001349200, NM_001349201, NM_001349202, NM_001349203, NM_001349204, NM_001349205, NM_001349206, NM_001349207, NM_001349208, NR_146080, NM_145693.1, NM_145693.2, NM_145693.3, NM_001261429.1, NM_001261427.1, NM_001261427.2, NM_001261428.1, NM_001261428.2, BC030537, BC030537.1, BC018071, NM_145693.4, NM_001261428.3
• UniProt ID: Q14693
• Summary: This gene encodes a magnesium-ion-dependent phosphatidic acid phosphohydrolase enzyme that catalyzes the penultimate step in triglyceride synthesis including the dephosphorylation of phosphatidic acid to yield diacylglycerol. Expression of this gene is required for adipocyte differentiation and it also functions as a nuclear transcriptional coactivator with some peroxisome proliferator-activated receptors to modulate expression of other genes involved in lipid metabolism. Mutations in this gene are associated with metabolic syndrome, type 2 diabetes, acute recurrent rhabdomyolysis, and autosomal recessive acute recurrent myoglobinuria (ARARM). This gene is also a candidate for several human lipodystrophy syndromes. [provided by RefSeq, Mar 2017]
• shRNA Design: These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
• Shipping: Ambient