TBLR1 (TBL1XR1) Human shRNA Plasmid Kit (Locus ID 79718)

SKU TR301196

TBL1XR1 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector, 5µg of each construct provided

Product Data

• Locus ID: 79718
• Synonyms: C21; DC42; IRA1; MRD41; TBLR1
• Vector: pRS
• E. coli Selection: Ampicillin
• Format: Retroviral plasmids
• Components: TBL1XR1 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 79718). 5µg purified plasmid DNA per construct; 29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free.
• RefSeq: NM_001321193, NM_001321194, NM_001321195, NM_024665, NM_024665.1, NM_024665.2, NM_024665.3, NM_024665.4, NM_024665.5, BC113421, BC034712, BC048298, BC060320, BC070134, BC092400, NM_024665.7
• UniProt ID: Q9BZK7
• Summary: This gene is a member of the WD40 repeat-containing gene family and shares sequence similarity with transducin (beta)-like 1X-linked (TBL1X). The protein encoded by this gene is thought to be a component of both nuclear receptor corepressor (N-CoR) and histone deacetylase 3 (HDAC 3) complexes, and is required for transcriptional activation by a variety of transcription factors. Mutations in these gene have been associated with some autism spectrum disorders, and one finding suggests that haploinsufficiency of this gene may be a cause of intellectual disability with dysmorphism. Mutations in this gene as well as recurrent translocations involving this gene have also been observed in some tumors. [provided by RefSeq, Mar 2016]
• shRNA Design: These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
• Shipping: Ambient