TBLR1 (TBL1XR1) (NM_024665) Human Recombinant Protein

CAT#: TP760864

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Purified recombinant protein of Human transducin (beta)-like 1 X-linked receptor 1 (TBL1XR1), full length, with N-terminal HIS tag, expressed in E. coli, 50ug



  View other "TBL1XR1" proteins (2)

USD 215.00


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    • 50 ug


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Product Data
Description Purified recombinant protein of Human transducin (beta)-like 1 X-linked receptor 1 (TBL1XR1), full length, with N-terminal HIS tag, expressed in E. coli, 50ug
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence A DNA sequence encoding human full-length TBL1XR1
Tag N-His
Predicted MW 55.4 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25mM Tris, pH8.0, 150mM NaCl, 10% glycerol, 1 % Sarkosyl.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Reference Data
RefSeq NP_078941
Locus ID 79718
Refseq Size 6550
Cytogenetics 3q26.32
Refseq ORF 1542
Synonyms C21; DC42; IRA1; MRD41; TBLR1
Summary This gene is a member of the WD40 repeat-containing gene family and shares sequence similarity with transducin (beta)-like 1X-linked (TBL1X). The protein encoded by this gene is thought to be a component of both nuclear receptor corepressor (N-CoR) and histone deacetylase 3 (HDAC 3) complexes, and is required for transcriptional activation by a variety of transcription factors. Mutations in these gene have been associated with some autism spectrum disorders, and one finding suggests that haploinsufficiency of this gene may be a cause of intellectual disability with dysmorphism. Mutations in this gene as well as recurrent translocations involving this gene have also been observed in some tumors. [provided by RefSeq, Mar 2016]
Protein Families Druggable Genome, Transcription Factors
Protein Pathways Wnt signaling pathway

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