Cxcl1 (NM_008176) Mouse Recombinant Protein

SKU TP723728

Purified recombinant protein of Mouse chemokine (C-X-C motif) ligand 1 (Cxcl1 / KC)

Product Data

• Species: Mouse
• Expression Host: E. coli
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  Mouse CXCL1, the region of Asn29-Lys96, from gene Accession# NM_008176.3
• Tag: Tag Free
• Predicted MW: 7.4 kDa
• Concentration: lot specific
• Purity: >98%, as determined by Coomassie stained SDS-PAGE.
• Buffer: 1 x PBS
• Bioactivity: Recombinant mouse CXCL1 (KC) chemoattracts Baf3-mCXCR2 transfectants in a dose-dependent manner. The ED50 for this effect is 0.1– 0.6 ng/mL.
• Endotoxin: Less than 0.01 ng per µg protein as determined by the LAL method
• Storage: Store at -80°C.
• Stability: Unopened vial can be stored between 2°C and 8°C for up to 2 weeks, at -20°C for up to 6 months, or at -70°C or below until the expiration date. Aliquots can be stored between 2°C and 8°C for up to one week and stored at -20°C or colder for up to 3 months. Avoid repeated freeze/thaw cycles.
• Shipping: Dry Ice

Reference Data

• RefSeq: NP_032202
• Locus ID: 14825
• UniProt ID: P12850
• Cytogenetics: 5 44.78 cM
• RefSeq Size: 964
• RefSeq ORF: 288
• Synonyms: F; Fsp; Gr; gro; Gro1; KC; Mg; Mgsa; N5; N51; Scyb; Scyb1
• Summary: This gene encodes a protein that is a member of the CXC subfamily of chemokines. Chemokines, which recruit and activate leukocytes, are classified by function (inflammatory or homeostatic) or by structure. This secretory protein is proposed to bind the G-protein coupled receptor chemokine (C-X-C motif) receptor 2 to recruit neutrophils. In mouse, deficiency of this gene is associated with colitis and with defects in immune cell recruitment to the lung. [provided by RefSeq, Apr 2013]