Interferon gamma (IFNG) (NM_000619) Human Recombinant Protein

CAT#: TP723709

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Purified recombinant protein of Human interferon, gamma (IFNG)


Product Datasheet for 'TP723709'


  View other "IFNG" proteins (8)

USD 145.00


Availability*
5 Days

Size
    • 10 ug


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Specifications

Product Data
Description Purified recombinant protein of Human interferon, gamma (IFNG)
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence Human IFN-gamma;, the region of Gln24-Gln166, from gene Accession# NM_000619
Tag Tag Free
Predicted MW 17 kDa
Concentration Protein formulated and vialed at >50 ug/mL in specified buffer
Purity Purity is >98%, as determined by Coomassie stained SDS-PAGE.
Buffer 20mM NaH2PO4, 150mM NaCl, pH7.2
Bioactivity The ED50 is 0.416 ng/ml, corresponding to a specific activity of 2.4 X10^6 units/mg, determined by a dose dependent stimulation of HT-29 cells.
Endotoxin Less than 0.01 ng per ug protein as determined by the LAL method
Storage Store at -80°C.
Stability Unopened vial can be stored between 2°C and 8°C for up to 2 weeks, at -20°C for up to 6 months, or at -70°C or below until the expiration date. Aliquots can be stored between 2°C and 8°C for up to one week and stored at -20°C or colder for up to 3 months. Avoid repeated freeze/thaw cycles.
Reference Data
RefSeq NP_000610
Locus ID 3458
Refseq Size 1240
Cytogenetics 12q15
Refseq ORF 498
Synonyms IFG; IFI
Summary This gene encodes a soluble cytokine that is a member of the type II interferon class. The encoded protein is secreted by cells of both the innate and adaptive immune systems. The active protein is a homodimer that binds to the interferon gamma receptor which triggers a cellular response to viral and microbial infections. Mutations in this gene are associated with an increased susceptibility to viral, bacterial and parasitic infections and to several autoimmune diseases. [provided by RefSeq, Dec 2015]
Protein Families Druggable Genome, Secreted Protein
Protein Pathways Allograft rejection, Cytokine-cytokine receptor interaction, Graft-versus-host disease, Jak-STAT signaling pathway, Natural killer cell mediated cytotoxicity, Proteasome, Regulation of autophagy, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, Type I diabetes mellitus

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Other Versions

Other products for "IFNG"
Frequently bought together (1)
IFNG mouse monoclonal antibody, clone OTI1G10 (formerly 1G10)
    • 100 ul

USD 379.00

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