FGF8 (NM_033163) Human Recombinant Protein

CAT#: TP723101

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Purified recombinant protein of Human fibroblast growth factor 8 (androgen-induced) (FGF8), transcript variant F.


 Product Datasheet for 'TP723101'

  View other "FGF8" proteins (5)

USD 240.00


Availability*
5 Days

Size
    • 25 ug


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Specifications

Product Data
Description Purified recombinant protein of Human fibroblast growth factor 8 (androgen-induced) (FGF8), transcript variant F.
Species Human
Expression Host E. coli
Tag Tag Free
Predicted MW 22.5 kDa
Concentration Resuspend the protein in the desired concentration in proper buffer
Purity >95% as determined by SDS-PAGE and Coomassie blue staining
Buffer Lyophilized from a 0.2 µM filtered solution of 20mM phosphate buffer,100mM NaCl, pH 7.2
Bioactivity Determined by a cell proliferation assay using Balb/c 3T3 cells. The expected ED50 is ≤ 5 ng/ml, corresponding to a specific activity of ≥ 2 x 105 units/mg.
Endotoxin Endotoxin level is < 0.1 ng/µg of protein (< 1 EU/µg)
Reference Data
RefSeq NP_149353
Locus ID 2253
Refseq Size 1107
Cytogenetics 10q24.32
Refseq ORF 732
Synonyms AIGF; FGF-8; HBGF-8; HH6; KAL6
Summary The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein is known to be a factor that supports androgen and anchorage independent growth of mammary tumor cells. Overexpression of this gene has been shown to increase tumor growth and angiogensis. The adult expression of this gene is restricted to testes and ovaries. Temporal and spatial pattern of this gene expression suggests its function as an embryonic epithelial factor. Studies of the mouse and chick homologs revealed roles in midbrain and limb development, organogenesis, embryo gastrulation and left-right axis determination. The alternative splicing of this gene results in four transcript variants. [provided by RefSeq, Jul 2008]
Protein Families Druggable Genome, Secreted Protein
Protein Pathways MAPK signaling pathway, Melanoma, Pathways in cancer, Regulation of actin cytoskeleton

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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