Alkaline Phosphatase (ALPP) (NM_001632) Human Recombinant Protein
CAT#: TP721056
Purified recombinant protein of Human alkaline phosphatase, placental (ALPP)
Product Images
Specifications
Product Data | |
Species | Human |
Expression Host | HEK293 |
Expression cDNA Clone or AA Sequence |
Ile23-Asp506
|
Tag | C-His |
Predicted MW | 53.7 kDa |
Purity | >95% as determined by SDS-PAGE and Coomassie blue staining |
Buffer | Provided lyophilized from a 0.2 μm filtered solution of 20 mM Tris-HCl, 150 mM NaCl |
Endotoxin | Endotoxin level is < 0.1 ng/µg of protein (< 1 EU/µg) |
Storage | Store at -80°C. |
Stability | Stable for at least 3 months from date of receipt under proper storage and handling conditions. |
Reference Data | |
RefSeq | NP_001623 |
Locus ID | 250 |
UniProt ID | P05187, B2R7C7 |
Cytogenetics | 2q37.1 |
Refseq Size | 2883 |
Refseq ORF | 1605 |
Synonyms | ALP; ALPI; IAP; PALP; PLAP; PLAP-1 |
Summary | The protein encoded by this gene is an alkaline phosphatase, a metalloenzyme that catalyzes the hydrolysis of phosphoric acid monoesters. It belongs to a multigene family composed of four alkaline phosphatase isoenzymes. The enzyme functions as a homodimer and has a catalytic site containing one magnesium and two zinc ions, which are required for its enzymatic function. One of the main sources of this enzyme is the liver, and thus, it's one of several indicators of liver injury in different clinical conditions. In pregnant women, this protein is primarily expressed in placental and endometrial tissue, however, strong ectopic expression has been detected in ovarian adenocarcinoma, serous cystadenocarcinoma, and other ovarian cancer cells. [provided by RefSeq, Aug 2020] |
Protein Pathways | Folate biosynthesis, Metabolic pathways |
Documents
FAQs |
SDS |
Resources
Recombinant Protein Resources |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
LC419831 | ALPP HEK293T cell transient overexpression lysate (as WB positive control) |
USD 134.00 |
|
LY419831 | Transient overexpression lysate of alkaline phosphatase, placental (Regan isozyme) (ALPP) |
USD 436.00 |
|
PH310504 | ALPP MS Standard C13 and N15-labeled recombinant protein (NP_001623) |
USD 3,255.00 |
|
TP310504 | Recombinant protein of human alkaline phosphatase, placental (Regan isozyme) (ALPP), 20 µg |
USD 867.00 |
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