Interferon gamma (IFNG) (NM_000619) Human Recombinant Protein

CAT#: TP720013

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Recombinant protein of human interferon, gamma (IFNG)


Product Datasheet for 'TP720013'


  View other "IFNG" proteins (8)

USD 300.00


Availability*
2 Weeks

Size
    • 10 ug


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Specifications

Product Data
Description Recombinant protein of human interferon, gamma (IFNG)
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence A DNA sequence from TrueORF clone, RC209993, encoding the mature peptide (Gln24-Gln166) of human IFNG
Tag Tag Free
Predicted MW 16.9 kDa
Concentration Resuspend the protein to the desired concentration in proper buffer.
Purity >95% as determined by SDS-PAGE and Coomassie blue staining
Buffer Lyophilized from a 0.2 µM filtered solution of 20mM Phosphate buffer, 150mM NaCl, pH 7.0.
Bioactivity Specific Activity is greater than 1.5 x 107 IU/mg as determined in a viral resistance assay using VSV-WISH cells.
Endotoxin < 0.1 EU per µg protein as determined by LAL test
Storage Store at -80°C.
Stability Stable for at least 6 months from date of receipt under proper storage and handling conditions.
Reference Data
RefSeq NP_000610
Locus ID 3458
Refseq Size 1240
Cytogenetics 12q15
Refseq ORF 498
Synonyms IFG; IFI
Summary This gene encodes a soluble cytokine that is a member of the type II interferon class. The encoded protein is secreted by cells of both the innate and adaptive immune systems. The active protein is a homodimer that binds to the interferon gamma receptor which triggers a cellular response to viral and microbial infections. Mutations in this gene are associated with an increased susceptibility to viral, bacterial and parasitic infections and to several autoimmune diseases. [provided by RefSeq, Dec 2015]
Protein Families Druggable Genome, Secreted Protein
Protein Pathways Allograft rejection, Cytokine-cytokine receptor interaction, Graft-versus-host disease, Jak-STAT signaling pathway, Natural killer cell mediated cytotoxicity, Proteasome, Regulation of autophagy, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, Type I diabetes mellitus

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Other Versions

Other products for "IFNG"
Frequently bought together (1)
IFNG mouse monoclonal antibody, clone OTI4D7 (formerly 4D7)
    • 100 ul

USD 379.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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