Alpha-crystallin A chain / CRYA1 (1-175) Mouse Protein

SKU AR03037PU-N

Alpha-crystallin A chain / CRYA1 (1-175) mouse recombinant protein, 0.1 mg

Product Data

• Species: Mouse
• Expression Host: E. coli
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  MDIAIHHPWI RRPFFPFHSP SRLFDQFFGE HLLESDLFST ATSLSPFYLR PPSFLRAPSW IDTGLSEMRL EKDRFSVNLD VKHFSPEELK VKVLGDVIEV HGKHEERQDE HGFISREFHR KYRIPADVDP LTITSSLSSD GVLTVNGPRK QVSGPERTIP ITREEKPAVA AAPKK
• Predicted MW: 20 kDa
• Concentration: lot specific
• Purity: >95% > 95 % by SDS PAGE
• Presentation State: Purified
• Buffer: Presentation State: Purified; State: Liquid; Buffer System: 20 mM Tris pH 8.0 and 10% glycerol
• Preparation: Liquid
• Protein Description: Recombinant mouse Crystallin alpha A / CRYAA
• Note: NCBI Accession No: NP_034094
• Storage: Store (in aliquots) at -20 °C. Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Shipping: Blue Ice

Reference Data

• RefSeq: NP_001265498
• Locus ID: 12954
• UniProt ID: A0A494B9Q6
• Cytogenetics: 17 17.09 cM
• Synonyms: CRYAA, HSPB4, Heat shock protein beta-4
• Summary: This gene encodes subunit a, one of two subunits of alpha-crystallin, which is a high molecular weight, soluble aggregate and is a member of the small heat shock protein (sHSP) family. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. It acts as a molecular chaperone and is the major protein in the eye lens, maintaining the transparency and refractive index of the lens. In mouse, deficiency in this gene is associated with smaller lenses and eyes and with increasing lens opacity with age. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]