HSP60 (active) Human Protein

CAT#: AR03019PU-N

HSP60 (active) human recombinant protein, 0.1 mg

Specifications

Product Data

• Species: Human
• Expression Host: E. coli
• Concentration: lot specific
• Purity: >90% pure as determined by SDS-PAGE analysis.
• Buffer: Presentation State: Aff - Purified
  State: Liquid Affinity purified protein.
  Buffer System: Na-Phosphate, pH 7.5 (20 mM), 150 mM NaCl, 10% Glycerol, 200 mM Imidazole
• Preparation: Liquid Affinity purified protein.
• Applications: ATPase Assay
  Western Blot Control.
  Binding Assays.
  ELISA reference standard.
• Protein Description: Recombinant Human Hsp60 Protein with ATPase activity, his-tagged
• Storage: Store (in aliquots) at -20°C.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: One year from despatch.

Reference Data

• RefSeq: NP_002147
• Locus ID: 3329
• UniProt ID: P10809, A0A024R3X4
• Cytogenetics: 2q33.1
• Synonyms: CPN60; GROEL; HLD4; HSP-60; HSP60; HSP65; HuCHA60; SPG13
• Summary: This gene encodes a member of the chaperonin family. The encoded mitochondrial protein may function as a signaling molecule in the innate immune system. This protein is essential for the folding and assembly of newly imported proteins in the mitochondria. This gene is adjacent to a related family member and the region between the 2 genes functions as a bidirectional promoter. Several pseudogenes have been associated with this gene. Two transcript variants encoding the same protein have been identified for this gene. Mutations associated with this gene cause autosomal recessive spastic paraplegia 13. [provided by RefSeq, Jun 2010]
• Protein Families: Druggable Genome, Stem cell - Pluripotency
• Protein Pathways: RNA degradation, Type I diabetes mellitus