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Twist1 Mouse Gene Knockout Kit (CRISPR)

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SKU
KN318498BN
Twist1 - mouse gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

Frequently Bought Together (3)

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Other products for "Twist1 or BC033434"

Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 mBFP-Neo donor, 1 scramble control
Vector mBFP-Neo
Target Symbol Twist1
Locus ID 22160
Components

KN318498G1, Twist1 gRNA vector 1 in pCas-Guide CRISPR vector

KN318498G2, Twist1 gRNA vector 2 in pCas-Guide CRISPR vector

KN318498BND, donor DNA containing left and right homologous arms and mBFP-Neo functional cassette.

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_011658
UniProt ID P26687
Synonyms bHLHa38; M-Twist; Pde; pdt; Ska10; Ska; Twist
Summary Basic helix-loop-helix (bHLH) transcription factors have been implicated in cell lineage determination and differentiation. This gene encodes a bHLH transcription factor that is evolutionarily conserved from invertebrates to humans, and was originally identified in Drosophila as an essential gene involved in early mesoderm development and dorsal-ventral patterning in the embryo. This protein plays a role in cancer by regulating the epithelial-mesenchymal transition (EMT), a process that is critical for metastasis initiation, and promoting tumor progression. Mutations in the human gene are associated with Saethre-Chotzen syndrome (SCS). Mice with heterozygous mutations in this gene exhibit cranofacial and structural defects similar to those seen in human SCS patients. provided by RefSeq, Sep 2015
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Other Versions
SKU Description Size Price
GA204498 Twist1 CRISPRa kit - CRISPR gene activation of mouse twist basic helix-loop-helix transcription factor 1 1 kit
$1,657.00
KN318498 Twist1 - mouse gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN318498LP Twist1 - mouse gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN318498RB Twist1 - mouse gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN518498 Twist1 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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