Jagged1 (JAG1) Human Gene Knockout Kit (CRISPR)
CAT#: KN210516LP
JAG1 - human gene knockout kit via CRISPR, HDR mediated
Functional Cassette: GFP-puro RFP-BSD mBFP-Neo
HDR-mediated knockout kit validation
USD 1,657.00
4 Weeks*
Specifications
Product Data | |
Format | 2 gRNA vectors, 1 Luciferase-Puro donor, 1 scramble control |
Donor DNA | Luciferase-Puro |
Symbol | Jagged1 |
Locus ID | 182 |
Components |
KN210516G1, Jagged1 gRNA vector 1 in pCas-Guide CRISPR vector KN210516G2, Jagged1 gRNA vector 2 in pCas-Guide CRISPR vector KN210516LPD, donor DNA containing left and right homologous arms and Luciferase-Puro functional cassette. GE100003, scramble sequence in pCas-Guide vector |
Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process. |
Reference Data | |
RefSeq | NM_000214 |
UniProt ID | P78504 |
Synonyms | AGS; AHD; AWS; CD339; HJ1; JAGL1 |
Summary | The jagged 1 protein encoded by JAG1 is the human homolog of the Drosophilia jagged protein. Human jagged 1 is the ligand for the receptor notch 1, the latter is involved in signaling processes. Mutations that alter the jagged 1 protein cause Alagille syndrome. Jagged 1 signalling through notch 1 has also been shown to play a role in hematopoiesis. [provided by RefSeq, Nov 2019] |
Documents
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FAQs |
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Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN210516 | JAG1 - human gene knockout kit via CRISPR, HDR mediated |
USD 1,657.00 |
|
KN210516BN | JAG1 - human gene knockout kit via CRISPR, HDR mediated |
USD 1,657.00 |
|
KN210516RB | JAG1 - human gene knockout kit via CRISPR, HDR mediated |
USD 1,657.00 |
|
KN410516 | JAG1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. |
USD 1,657.00 |
|
GA100128 | JAG1 CRISPRa kit - CRISPR gene activation of human jagged canonical Notch ligand 1 |
USD 1,657.00 |
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