VCP (NM_007126) Human Tagged ORF Clone Lentiviral Particle
CAT#: RC211130L4V
- LentiORF®
Lenti ORF particles, VCP (mGFP-tagged) - Human valosin containing protein (VCP), 200ul, >10^7 TU/mL
Lentiviral Particles: DDK DDK w/ Puro mGFP
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Specifications
Product Data | |
Type | Human Tagged ORF Clone Lentiviral Particle |
Tag | mGFP |
Symbol | VCP |
Synonyms | CDC48; FTDALS6; p97; TERA |
Mammalian Cell Selection | Puromycin |
Vector | pLenti-C-mGFP-P2A-Puro |
ACCN | NM_007126 |
ORF Size | 2418 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC211130).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_007126.2 |
RefSeq Size | 3859 bp |
RefSeq ORF | 2421 bp |
Locus ID | 7415 |
UniProt ID | P55072 |
Cytogenetics | 9p13.3 |
Domains | cdc48_N, AAA, AAA |
MW | 89.3 kDa |
Gene Summary | This gene encodes a member of the AAA ATPase family of proteins. The encoded protein plays a role in protein degradation, intracellular membrane fusion, DNA repair and replication, regulation of the cell cycle, and activation of the NF-kappa B pathway. This protein forms a homohexameric complex that interacts with a variety of cofactors and extracts ubiquitinated proteins from lipid membranes or protein complexes. Mutations in this gene cause IBMPFD (inclusion body myopathy with paget disease of bone and frontotemporal dementia), ALS (amyotrophic lateral sclerosis) and Charcot-Marie-Tooth disease in human patients. [provided by RefSeq, Aug 2017] |
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