GADD45A (NM_001924) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC204005L1V

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  • LentiORF®

Lenti ORF particles, GADD45A (Myc-DDK tagged) - Human growth arrest and DNA-damage-inducible, alpha (GADD45A), transcript variant 1, 200ul, >10^7 TU/mL


Product Datasheet for 'RC204005L1V'


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USD 820.00


Availability*
3 Weeks

Size
    • 200 ul


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Specifications

Product Data
Product Name GADD45A (NM_001924) Human Tagged ORF Clone Lentiviral Particle
Type Human Tagged ORF Clone Lentiviral Particle
Tag Myc-DDK
Symbol GADD45A
Synonyms DDIT1; GADD45
Vector pLenti-C-Myc-DDK
Tag Myc-DDK
ACCN NM_001924
ORF Size 495 bp
Sequence Data
The ORF insert of this clone is exactly the same as(RC204005).
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Reference Data
RefSeq NM_001924.2, NP_001915.1
RefSeq Size 1398 bp
RefSeq ORF 498 bp
Locus ID 1647
Cytogenetics 1p31.3
Domains Ribosomal_L7Ae
Protein Families Druggable Genome, Stem cell - Pluripotency
Protein Pathways Cell cycle, MAPK signaling pathway, p53 signaling pathway
MW 18.3 kDa
Gene Summary This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The protein encoded by this gene responds to environmental stresses by mediating activation of the p38/JNK pathway via MTK1/MEKK4 kinase. The DNA damage-induced transcription of this gene is mediated by both p53-dependent and -independent mechanisms. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Dec 2010]
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