GADD45A Mouse Monoclonal Antibody [Clone ID: OTI1C9]

CAT#: TA507370

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GADD45A mouse monoclonal antibody, clone OTI1C9 (formerly 1C9)


Product Datasheet for 'TA507370'


  View other "OTI1C9" antibodies (2)

USD 379.00


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Specifications

Product Data
Clone Name OTI1C9
Applications WB
Recommended Dilution WB 1:4000
Reactivity Human
Host Mouse
Isotype IgG2b
Clonality Monoclonal
Immunogen Full length human recombinant protein of human GADD45A(NP_001915) produced in HEK293T cell.
Formulation PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration 1 mg/ml
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Predicted Protein Size 18.2 kDa
Gene Name growth arrest and DNA damage inducible alpha
Background This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The protein encoded by this gene responds to environmental stresses by mediating activation of the p38/JNK pathway via MTK1/MEKK4 kinase. The DNA damage-induced transcription of this gene is mediated by both p53-dependent and -independent mechanisms. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Dec 2010]
Synonyms DDIT1; GADD45
Reference Data
Protein Families Druggable Genome, Stem cell - Pluripotency
Protein Pathways Cell cycle, MAPK signaling pathway, p53 signaling pathway

Other Versions

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