PVRL4 (NECTIN4) (NM_030916) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC203431L3V

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  • LentiORF®

Lenti ORF particles, PVRL4 (Myc-DDK tagged) - Human poliovirus receptor-related 4 (PVRL4), 200ul, >10^7 TU/mL



USD 1,020.00


Availability*
3 Weeks

Size
    • 200 ul


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Specifications

Product Data
Type Human Tagged ORF Clone Lentiviral Particle
Tag Myc-DDK
Symbol NECTIN4
Synonyms EDSS1; LNIR; nectin-4; PRR4; PVRL4
Mammalian Cell Selection Puromycin
Vector pLenti-C-Myc-DDK-P2A-Puro
ACCN NM_030916
ORF Size 1530 bp
Sequence Data
The ORF insert of this clone is exactly the same as(RC203431).
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Reference Data
RefSeq NM_030916.1
RefSeq Size 3520 bp
RefSeq ORF 1533 bp
Locus ID 81607
UniProt ID Q96NY8
Cytogenetics 1q23.3
Domains ig, IGc2, IG
Protein Families Druggable Genome, Transmembrane
Protein Pathways Adherens junction
MW 55.5 kDa
Gene Summary This gene encodes a member of the nectin family. The encoded protein contains two immunoglobulin-like (Ig-like) C2-type domains and one Ig-like V-type domain. It is involved in cell adhesion through trans-homophilic and -heterophilic interactions. It is a single-pass type I membrane protein. The soluble form is produced by proteolytic cleavage at the cell surface by the metalloproteinase ADAM17/TACE. The secreted form is found in both breast tumor cell lines and breast tumor patients. Mutations in this gene are the cause of ectodermal dysplasia-syndactyly syndrome type 1, an autosomal recessive disorder. Alternatively spliced transcript variants have been found but the full-length nature of the variant has not been determined.[provided by RefSeq, Jan 2011]
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