Histone H2A.X (H2AFX) (NM_002105) Human Tagged ORF Clone Lentiviral Particle
CAT#: RC201434L4V
- LentiORF®
Lenti ORF particles, H2AFX (mGFP-tagged) - Human H2A histone family, member X (H2AFX), 200ul, >10^7 TU/mL
Lentiviral Particles: DDK DDK w/ Puro mGFP
AAV Particle: DDK
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Specifications
Product Data | |
Type | Human Tagged ORF Clone Lentiviral Particle |
Tag | mGFP |
Symbol | Histone H2A.X |
Synonyms | H2A.X; H2A/X; H2AFX |
Mammalian Cell Selection | Puromycin |
Vector | pLenti-C-mGFP-P2A-Puro |
ACCN | NM_002105 |
ORF Size | 429 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC201434).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_002105.1 |
RefSeq Size | 1651 bp |
RefSeq ORF | 432 bp |
Locus ID | 3014 |
UniProt ID | P16104 |
Cytogenetics | 11q23.3 |
Domains | H2A, histone |
Protein Families | Druggable Genome |
Protein Pathways | Systemic lupus erythematosus |
MW | 15.1 kDa |
Gene Summary | Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a replication-independent histone that is a member of the histone H2A family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif. [provided by RefSeq, Oct 2015] |
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