PDZK1 (NM_002614) Human Tagged ORF Clone Lentiviral Particle
CAT#: RC200444L4V
- LentiORF®
Lenti ORF particles, PDZK1 (mGFP-tagged) - Human PDZ domain containing 1 (PDZK1), transcript variant 1, 200ul, >10^7 TU/mL
Lentiviral Particles: DDK DDK w/ Puro mGFP
AAV Particle: DDK
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Specifications
Product Data | |
Type | Human Tagged ORF Clone Lentiviral Particle |
Tag | mGFP |
Symbol | PDZK1 |
Synonyms | CAP70; CLAMP; NHERF-3; NHERF3; PDZD1 |
Mammalian Cell Selection | Puromycin |
Vector | pLenti-C-mGFP-P2A-Puro |
ACCN | NM_002614 |
ORF Size | 1557 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC200444).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_002614.3 |
RefSeq Size | 2301 bp |
RefSeq ORF | 1560 bp |
Locus ID | 5174 |
UniProt ID | Q5T2W1 |
Cytogenetics | 1q21.1 |
Domains | PDZ |
MW | 57.1 kDa |
Gene Summary | This gene encodes a PDZ domain-containing scaffolding protein. PDZ domain-containing molecules bind to and mediate the subcellular localization of target proteins. The encoded protein mediates the localization of cell surface proteins and plays a critical role in cholesterol metabolism by regulating the HDL receptor, scavenger receptor class B type 1. Single nucleotide polymorphisms in this gene may be associated with metabolic syndrome, and overexpression of this gene may play a role in drug resistance of multiple myeloma. Pseudogenes of this gene are located on the long arm of chromosome 1. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011] |
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