Casr (NM_013803) Mouse Tagged ORF Clone Lentiviral Particle
CAT#: MR223303L2V
- LentiORF®
Lenti ORF particles, Casr (GFP-tagged) - Mouse calcium-sensing receptor (Casr), 200ul, >10^7 TU/mL
Lentiviral Particles: DDK DDK w/ Puro mGFP w/ Puro
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Specifications
Product Data | |
Type | Mouse Tagged ORF Clone Lentiviral Particle |
Tag | mGFP |
Symbol | Casr |
Synonyms | CaR; Gprc2a |
Mammalian Cell Selection | None |
Vector | pLenti-C-mGFP |
ACCN | NM_013803 |
ORF Size | 3237 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(MR223303).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_013803.2 |
RefSeq Size | 4549 bp |
RefSeq ORF | 3240 bp |
Locus ID | 12374 |
UniProt ID | Q9QY96 |
Cytogenetics | 16 25.57 cM |
Gene Summary | G-protein-coupled receptor that senses changes in the extracellular concentration of calcium ions and plays a key role in maintaining calcium homeostasis (By similarity). Senses fluctuations in the circulating calcium concentration and modulates the production of parathyroid hormone (PTH) in parathyroid glands (PubMed:7493018). The activity of this receptor is mediated by a G-protein that activates a phosphatidylinositol-calcium second messenger system (By similarity). The G-protein-coupled receptor activity is activated by a co-agonist mechanism: aromatic amino acids, such as Trp or Phe, act concertedly with divalent cations, such as calcium or magnesium, to achieve full receptor activation (By similarity).[UniProtKB/Swiss-Prot Function] |
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