Casr (NM_013803) Mouse Tagged ORF Clone Lentiviral Particle

CAT#: MR223303L3V

  • LentiORF®

Lenti ORF particles, Casr (Myc-DDK-tagged) - Mouse calcium-sensing receptor (Casr), 200ul, >10^7 TU/mL

ORF Plasmid: DDK tGFP

Lentiviral Particles: DDK DDK w/ Puro mGFP mGFP w/ Puro



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USD 1,959.00

2 Weeks*

Size
    • 200 ul

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Specifications

Product Data
Type Mouse Tagged ORF Clone
Tag Myc-DDK
Symbol Casr
Synonyms CaR; Gprc2a
Mammalian Cell Selection Puromycin
Vector pLenti-C-Myc-DDK-P2A-Puro
ACCN NM_013803
ORF Size 3237 bp
Sequence Data
The ORF insert of this clone is exactly the same as(MR223303).
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Reference Data
RefSeq NM_013803.2
RefSeq Size 4549 bp
RefSeq ORF 3240 bp
Locus ID 12374
UniProt ID Q9QY96
Cytogenetics 16 25.57 cM
Gene Summary G-protein-coupled receptor that senses changes in the extracellular concentration of calcium ions and plays a key role in maintaining calcium homeostasis (By similarity). Senses fluctuations in the circulating calcium concentration and modulates the production of parathyroid hormone (PTH) in parathyroid glands (PubMed:7493018). The activity of this receptor is mediated by a G-protein that activates a phosphatidylinositol-calcium second messenger system (By similarity). The G-protein-coupled receptor activity is activated by a co-agonist mechanism: aromatic amino acids, such as Trp or Phe, act concertedly with divalent cations, such as calcium or magnesium, to achieve full receptor activation (By similarity).[UniProtKB/Swiss-Prot Function]

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