Arhgap24 (BC023344) Mouse Tagged ORF Clone Lentiviral Particle

CAT#: MR209791L3V

  • LentiORF®

Lenti ORF particles, Arhgap24 (Myc-DDK-tagged) - Mouse Rho GTPase activating protein 24 (cDNA clone MGC:32510 IMAGE:5064885), 200ul, >10^7 TU/mL

ORF Plasmid: DDK tGFP

Lentiviral Particles: DDK w/ Puro mGFP w/ Puro


Biosafety Sheet


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USD 1,159.00

5 Weeks*

Size
    • 200 ul

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Specifications

Product Data
Type Mouse Tagged ORF Clone Lentiviral Particle
Tag Myc-DDK
Symbol Arhgap24
Synonyms MGC38749
Mammalian Cell Selection Puromycin
Vector pLenti-C-Myc-DDK-P2A-Puro
ACCN BC023344
ORF Size 1962 bp
Sequence Data
The ORF insert of this clone is exactly the same as(MR209791).
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Reference Data
RefSeq BC023344, AAH23344
RefSeq Size 2732 bp
RefSeq ORF 1964 bp
Locus ID 231532
Cytogenetics 5 E5
Gene Summary Rho GTPase-activating protein involved in cell polarity, cell morphology and cytoskeletal organization. Acts as a GTPase activator for the Rac-type GTPase by converting it to an inactive GDP-bound state. Controls actin remodeling by inactivating Rac downstream of Rho leading to suppress leading edge protrusion and promotes cell retraction to achieve cellular polarity. Able to suppress RAC1 and CDC42 activity in vitro. Overexpression induces cell rounding with partial or complete disruption of actin stress fibers and formation of membrane ruffles, lamellipodia, and filopodia. Isoform 2 is a vascular cell-specific GAP involved in modulation of angiogenesis (By similarity).[UniProtKB/Swiss-Prot Function]

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