Atg5 (NM_053069) Mouse Tagged ORF Clone Lentiviral Particle
CAT#: MR203691L3V
- LentiORF®
Lenti ORF particles, Atg5 (Myc-DDK-tagged) - Mouse autophagy-related 5 (yeast) (Atg5), 200ul, >10^7 TU/mL
Lentiviral Particles: mGFP w/ Puro
AAV Particle: DDK
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Specifications
Product Data | |
Type | Mouse Tagged ORF Clone Lentiviral Particle |
Tag | Myc-DDK |
Symbol | Atg5 |
Synonyms | 2010107M05Rik; 3110067M24Rik; Ap; Apg5l; Atg5l; AW319544; C88337; Pad; Paddy |
Mammalian Cell Selection | Puromycin |
Vector | pLenti-C-Myc-DDK-P2A-Puro |
ACCN | NM_053069 |
ORF Size | 828 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(MR203691).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_053069.5 |
RefSeq Size | 2352 bp |
RefSeq ORF | 828 bp |
Locus ID | 11793 |
UniProt ID | Q99J83 |
Cytogenetics | 10 23.24 cM |
Gene Summary | The protein encoded by this gene, in combination with autophagy protein 12, functions as an E1-like activating enzyme in a ubiquitin-like conjugating system. The encoded protein is involved in several cellular processes, including autophagic vesicle formation, mitochondrial quality control after oxidative damage, negative regulation of the innate antiviral immune response, lymphocyte development and proliferation, MHC II antigen presentation, adipocyte differentiation, and apoptosis. Two transcript variants encoding different protein isoforms have been found for this gene. [provided by RefSeq, Sep 2015] |
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