FBXO4 (NM_012176) Human Untagged Clone

CAT#: SC320120

FBXO4 (untagged)-Human F-box protein 4 (FBXO4), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: FBXO4
• Synonyms: FBX4
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_012176.2 CGTCACCCACGCTGCGGGCAAGCCATGGCGGGAAGCGAGCCGCGCAGCGGAACAAACTCG
  CCGCCGCCGCCCTTCAGCGACTGGGGCCGCCTGGAGGCGGCCATCCTCAGCGGCTGGAAG
  ACCTTCTGGCAGTCAGTGAGCAAGGAGAGGGTGGCGCGTACGACCTCACGGGAGGAGGTG
  GATGAGGCGGCCAGCACCCTGACGCGGCTGCCGATTGATGTACAGCTATATATTTTGTCC
  TTTCTTTCACCTCATGATCTGTGTCAGTTGGGAAGTACAAATCATTATTGGAATGAAACT
  GTAAGAGATCCAATTCTGTGGAGATACTTTTTGTTGAGGGATCTTCCTTCTTGGTCTTCT
  GTTGACTGGAAGTCTCTTCCAGATCTAGAAATCTTAAAAAAGCCTATATCTGAGGTCACT
  GATGGTGCATTTTTTGACTACATGGCAGTCTATAGAATGTGCTGTCCATACACAAGAAGA
  GCTTCAAAATCCAGCCGTCCTATGTATGGAGCTGTCACTTCTTTTTTACACTCCCTGATC
  ATTCAGAATGAACCACGATTTGCTATGTTTGGACCAGGTTTGGAAGAATTGAATACCTCT
  TTGGTGTTGAGCTTGATGTCTTCAGAGGAACTTTGCCCAACAGCTGGTTTGCCTCAGAGG
  CAGATTGATGGTATTGGATCAGGAGTCAATTTTCAGTTGAACAACCAACATAAATTCAAC
  ATTCTAATCTTATATTCAACTACCAGAAAGGAAAGAGATAGAGCAAGGGAAGAGCATACA
  AGTGCAGTTAACAAGATGTTCAGTCGACACAATGAAGGTGATGATCAACAAGGAAGCCGG
  TACAGTGTGATTCCACAGATTCAAAAAGTGTGTGAAGTTGTAGATGGGTTCATCTATGTT
  GCAAATGCTGAAGCTCATAAAAGACATGAATGGCAAGATGAATTTTCTCATATTATGGCA
  ATGACAGATCCAGCCTTTGGGTCTTCGGGAAGACCATTGTTGGTTTTATCTTGTATTTCT
  CAAGGGGATGTAAAAAGAATGCCCTGTTTTTATTTGGCTCATGAGCTGCATCTGAATCTT
  CTAAATCACCCATGGCTGGTCCAGGATACAGAGGCTGAAACTCTGACTGGTTTTTTGAAT
  GGCATTGAGTGGATTCTTGAAGAAGTGGAATCTAAGCGTGCAAGATGATTCTCTTTTCAG
  ATCTTGGGAACTGAAACCATTTGAAATTTATTACTAAGGTCGTGATGTGAATATTTGCTC
  AGTCAGCCCACCTTGTCCTGCCTTTTTGCAGATAGGCTTTCATTTGGACAGCTATAACTG
  CTGTGTTTTTTATATTATTTTTACTCTTTACCATAAATCAATTACAAGAAAAGAGTTTCA
  GTCCTAGTATTTAGCCCCAAAATGAACCTTTAAACATTTTTTTGGTAATTTTTATATTTT
  CTGTCTTTTTAAAAATATTAAATTCTGGAAAAAACAAAAAAAAAAAAAAAA
• Restriction Sites: Please inquire
• ACCN: NM_012176
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_012176.2, NP_036308.1
• RefSeq Size: 1523 bp
• RefSeq ORF: 1164 bp
• Locus ID: 26272
• UniProt ID: Q9UKT5
• Cytogenetics: 5p13.1
• Protein Families: Druggable Genome
• Protein Pathways: Ubiquitin mediated proteolysis
• Gene Summary: This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014]
  Transcript Variant: This variant (1) encodes the longest isoform (1).