RAB12 (NM_001025300) Human Untagged Clone

CAT#: SC317349

RAB12 (untagged)-Human RAB12, member RAS oncogene family (RAB12)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: RAB12
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_001025300 edited
  GCTGCCGCTACTGCGGAGTAGCTGCTTCCCTTCCTCCTCTCCCGGCGGCGGCGGCGGCAG
  CGGCGGAGGAGGAGGAGGAGGGGACCCGGGCGCAGAGAGCCGGCCGGCGGCGCAGTTGCA
  GCGCGGAGCCCACGGGCCGCCGGGGCCGCTCCAGCGGGCGGAAGCCGAGCCCGGGGCCGA
  CCCCCCGCGCGCGGCGGAGGCCGAGGGGGCGCCGGGGCCCGGGGCGCGCAGCCGGGGGGC
  GGGCGGCGGCGGGCGGCGGGCCGAGCGGGAGCCGCATGCGTGTATGGATCCGGGCGCCGC
  GCTGCAGAGGCGGGCCGGGGGCGGCGGCGGTCTGGGCGCGGGCTCCCCGGCGCTGTCGGG
  CGGCCAGGGCCGCCGGAGGAAGCAGCCCCCCAGGCCGGCCGACTTCAAGTTGCAGGTCAT
  CATTATCGGCTCCCGCGGCGTGGGCAAGACCAGCCTGATGGAGCGCTTCACCGACGACAC
  CTTCTGCGAGGCCTGCAAGTCCACCGTGGGTGTTGACTTCAAAATCAAAACTGTAGAGCT
  AAGAGGAAAGAAAATTAGATTACAGATCTGGGACACAGCAGGTCAGGAGAGATTCAACAG
  CATTACCTCAGCTTATTACAGAAGTGCCAAGGGGATCATATTAGTATATGATATCACTAA
  GAAGGAGACATTTGATGATTTGCCGAAATGGATGAAGATGATTGATAAGTATGCTTCAGA
  AGATGCAGAGCTTCTCTTAGTTGGAAATAAGTTGGACTGTGAAACGGACAGAGAAATCAC
  CAGGCAGCAGGGGGAAAAGTTTGCACAGCAGATCACTGGGATGCGGTTCTGTGAAGCAAG
  TGCCAAGGATAACTTCAATGTGGACGAGATATTTTTGAAACTTGTCGATGACATTCTGAA
  AAAGATGCCTCTGGATATTTTAAGGAATGAGTTGTCCAATAGTATCCTGTCGTTACAACC
  AGAGCCTGAGATACCGCCAGAACTGCCTCCACCAAGACCACATGTCCGATGCTGTTGATT
  TCCTACTTTGGAGACAAAGTGGAAATGATTCCTGGAAAGGGGAAAAAACGTTCTATTCTG
  CACTACAATCATTTTGACAATTTCCTTTCGCACTTTGTAATCCAAGTCAGAGCTATACAC
  TAACTTGTAAATATGCATATATGCAATCCTGGGTAAGTTTTGGTTATAAGTTACCTATTT
  CCCTCCAAATTATTATATTTCATTCATTACCCCAGTGTCTAGTGTACATACACTGGGAAA
  CCTAGTACTTCTAATATGAAGAATGGGAGAAATGAAAGGTATAATGTTTCTTGAAATAAA
  TAATATAATTGTCCTTATTAATTATATTATGAGGACAGAAGATATTCTGATAAGAGAGAA
  CGTGGTGCTTTGCTTACCGTTTTAAAGAAAATTTGTAAAACTAAAGACTTTTTGAAAAAA
  AGCTATCTTAAGTGCTTTTTCTTTATTTACAAGACATTTCCCCCAGTGGTAGCATCTGAA
  GTATTGGAGTGTTTCTGCCACGAAGCAAAGCTCCATTCATGGCCGTCATGGAAGGTTATT
  TATTAATGTTACATAATGGTAGAATATTACTAGTTAGAGGGTTGGATTTGACTTGGTCCT
  AAGGCCACAGAATCTCTCTCATGGCTTCCTAAGGGATGTACCTTTATGCTTTTAAGAACT
  ACAAAGATTCAATAAAGAAAGAAATGTTTTTGAAAAAAAAAAAAAAAAAAAAAAAAAAAA
  AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
  AAAAAAAA
  
• Restriction Sites: Please inquire
• ACCN: NM_001025300
• Insert Size: 1800 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: The ORF of this clone has been fully sequenced and found to be a perfect match to NM_001025300.2.
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001025300.2, NP_001020471.2
• RefSeq Size: 2138 bp
• RefSeq ORF: 735 bp
• Locus ID: 201475
• UniProt ID: Q6IQ22
• Cytogenetics: 18p11.22
• Gene Summary: The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. That Rab may play a role in protein transport from recycling endosomes to lysosomes regulating, for instance, the degradation of the transferrin receptor. Involved in autophagy (By similarity).[UniProtKB/Swiss-Prot Function]