LI Cadherin (CDH17) (NM_004063) Human Untagged Clone

CAT#: SC316998

CDH17 (untagged)-Human cadherin 17, LI cadherin (liver-intestine) (CDH17), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: LI Cadherin
• Synonyms: CDH16; HPT-1; HPT1
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_004063 edited
  GGAAGAAAAGGACTTTTAACCACCATTTTGTGACTTACAGAAAGGAATTTGAATAAAGAA
  AACTATGATACTTCAGGCCCATCTTCACTCCCTGTGTCTTCTTATGCTTTATTTGGCAAC
  TGGATATGGCCAAGAGGGGAAGTTTAGTGGACCCCTGAAACCCATGACATTTTCTATTTA
  TGAAGGCCAAGAACCGAGTCAAATTATATTCCAGTTTAAGGCCAATCCTCCTGCTGTGAC
  TTTTGAACTAACTGGGGAGACAGACAACATATTTGTGATAGAACGGGAGGGACTTCTGTA
  TTACAACAGAGCCTTGGACAGGGAAACAAGATCTACTCACAATCTCCAGGTTGCAGCCCT
  GGACGCTAATGGAATTATAGTGGAGGGTCCAGTCCCTATCACCATAAAAGTGAAGGACAT
  CAACGACAATCGACCCACGTTTCTCCAGTCAAAGTACGAAGGCTCAGTAAGGCAGAACTC
  TCGCCCAGGAAAGCCCTTCTTGTATGTCAATGCCACAGACCTGGATGATCCGGCCACTCC
  CAATGGCCAGCTTTATTACCAGATTGTCATCCAGCTTCCCATGATCAACAATGTCATGTA
  CTTTCAGATCAACAACAAAACGGGAGCCATCTCTCTTACCCGAGAGGGATCTCAGGAATT
  GAATCCTGCTAAGAATCCTTCCTATAATCTGGTGATCTCAGTGAAGGACATGGGAGGCCA
  GAGTGAGAATTCCTTCAGTGATACCACATCTGTGGATATCATAGTGACAGAGAATATTTG
  GAAAGCACCAAAACCTGTGGAGATGGTGGAAAACTCAACTGATCCTCACCCCATCAAAAT
  CACTCAGGTGCGGTGGAATGATCCCGGTGCACAATATTCCTTAGTTGACAAAGAGAAGCT
  GCCAAGATTCCCATTTTCAATTGACCAGGAAGGAGATATTTACGTGACTCAGCCCTTGGA
  CCGAGAAGAAAAGGATGCATATGTTTTTTATGCAGTTGCAAAGGATGAGTACGGAAAACC
  ACTTTCATATCCGCTGGAAATTCATGTAAAAGTTAAAGATATTAATGATAATCCACCTAC
  ATGTCCGTCACCAGTAACCGTATTTGAGGTCCAGGAGAATGAACGACTGGGTAACAGTAT
  CGGGACCCTTACTGCACATGACAGGGATGAAGAAAATACTGCCAACAGTTTTCTAAACTA
  CAGGATTGTGGAGCAAACTCCCAAACTTCCCATGGATGGACTCTTCCTAATCCAAACCTA
  TGCTGGAATGTTACAGTTAGCTAAACAGTCCTTGAAGAAGCAAGATACTCCTCAGTACAA
  CTTAACGATAGAGGTGTCTGACAAAGATTTCAAGACCCTTTGTTTTGTGCAAATCAACGT
  TATTGATATCAATGATCAGATCCCCATCTTTGAAAAATCAGATTATGGAAACCTGACTCT
  TGCTGAAGACACAAACATTGGGTCCACCATCTTAACCATCCAGGCCACTGATGCTGATGA
  GCCATTTACTGGGAGTTCTAAAATTCTGTATCATATCATAAAGGGAGACAGTGAGGGACG
  CCTGGGGGTTGACACAGATCCCCATACCAACACCGGATATGTCATAATTAAAAAGCCTCT
  TGATTTTGAAACAGCAGCTGTTTCCAACATTGTGTTCAAAGCAGAAAATCCTGAGCCTCT
  AGTGTTTGGTGTGAAGTACAATGCAAGTTCTTTTGCCAAGTTCACGCTTATTGTGACAGA
  TGTGAATGAAGCACCTCAATTTTCCCAACACGTATTCCAAGCGAAAGTCAGTGAGGATGT
  AGCTATAGGCACTAAAGTGGGCAATGTGACTGCCAAGGATCCAGAAGGTCTGGACATAAG
  CTATTCACTGAGGGGAGACACAAGAGGTTGGCTTAAAATTGACCACGTGACTGGTGAGAT
  CTTTAGTGTGGCTCCATTGGACAGAGAAGCCGGAAGTCCATATCGGGTACAAGTGGTGGC
  CACAGAAGTAGGGGGGTCTTCCTTAAGCTCTGTGTCAGAGTTCCACCTGATCCTTATGGA
  TGTGAATGACAACCCTCCCAGGCTAGCCAAGGACTACACGGGCTTGTTCTTCTGCCATCC
  CCTCAGTGCACCTGGAAGTCTCATTTTCGAGGCTACTGATGATGATCAGCACTTATTTCG
  GGGTCCCCATTTTACATTTTCCCTCGGCAGTGGAAGCTTACAAAACGACTGGGAAGTTTC
  CAAAATCAATGGTACTCATGCCCGACTGTCTACCAGGCACACAGACTTTGAGGAGAGGGC
  GTATGTCGTCTTGATCCGCATCAATGATGGGGGTCGGCCACCCTTGGAAGGCATTGTTTC
  TTTACCAGTTACATTCTGCAGTTGTGTGGAAGGAAGTTGTTTCCGGCCAGCAGGTCACCA
  GACTGGGATACCCACTGTGGGCATGGCAGTTGGTATACTGCTGACCACCCTTCTGGTGAT
  TGGTATAATTTTAGCAGTTGTGTTTATCCGCATAAAGAAGGATAAAGGCAAAGATAATGT
  TGAAAGTGCTCAAGCATCTGAAGTCAAACCTCTGAGAAGCTGAATTTGAAAAGGAATGTT
  TGAATTTATATAGCAAGTGCTATTTCAGCAACAACCATCTCATCCTATTACTTTTCATCT
  AACGTGCATTATAATTTTTTAAACAGATATTCCCTCTTGTCCTTTAATATTTGCTAAATA
  TTTCTTTTTTGAGGTGGAGTCTTGCTCTGTCGCCCAGGCTGGAGTACAGTGGTGTGATCC
  CAGCTCACTGCAACCTCCGCCTCCTGGGTTCACATGATTCTCCTGCCTCAGCTTCCTAAG
  TAGCTGGGTTTACAGGCACCCACCACCATGCCCAGCTAATTTTTGTATTTTTAATAGAGA
  CGGGGTTTCGCCATTTGGCCAGGCTGGTCTTGAACTCCTGACGTCAAGTGATCTGCCTGC
  CTTGGTCTCCCAATACAGGCATGAACCACTGCACCCACCTACTTAGATATTTCATGTGCT
  ATAGACATTAGAGAGATTTTTCATTTTTCCATGACATTTTTCCTCTCTGCAAATGGCTTA
  GCTACTTGTGTTTTTCCCTTTTGGGGCAAGACAGACTCATTAAATATTCTGTACATTTTT
  TCTTTATCAAGGGGGAAAAAAAAAAAAAAAAAAAAAAAAAAAA
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_004063 unedited
  GACACTTGTATACGACTCCTATAGGGCGGCCGCGAATTCGGCACCAGGAAGAAAAGGACT
  TTTAACCACCATTTTGTGACTTACAGAAAGGAATTTGAATAAAGAAAACTATGATACTTC
  AGGCCCATCTTCACTCCCTGTGTCTTCTTATGCTTTATTTGGCAACTGGATATGGCCAAG
  AGGGGAAGTTTAGTGGACCCCTGAAACCCATGACATTTTCTATTTATGAAGGCCAAGAAC
  CGAGTCAAATTATATTCCAGTTTAAGGCCAATCCTCCTGCTGTGACTTTTGAACTAACTG
  GGGAGACAGACAACATATTTGTGATAGAACGGGAGGGACTTCTGTATTACAACAGAGCCT
  TGGACAGGGAAACAAGATCTACTCACAATCTCCAGGTTGCAGCCCTGGACGCTAATGGAA
  TTATAGTGGAGGGTCCAGTCCCTATCACCATAAAAGTGAAGGACATCAACGACAATCGAC
  CCACGTTTCTCCAGTCAAAGTACGAAGGCTCAGTAAGGCAGAACTCTCGCCCAGGAAAGC
  CCTTCTTGTATGTCAATGCCACAGACCTGGATGATCCGGCCACTCCCAATGGCCAGCTTT
  ATTACCAGATTGTCATCCAGCTTCCCATGATCAACAATGTCATGTACTTTCAGATCAACA
  ACAAAACGGGAGCCATCTCTCTTACCCGAGAGGGATCTCAGAATTGAATCCTGCTAAGAA
  TCCTTCCTATAATCTGGTGATCTCAGTGAAGGACATGGGAGCCAGAGTGAGAATTCCTTC
  AGTGATACCACATCTGTGGATATCATAGTGACAGAGATATTTGGAAAGCACCAAACCTGT
  GAGATGTGAAACTCACTGATCCTCACCCCATCAAATCACTCAGTGGCGGTGGATGATCCC
  GGTGCACAATATTCCTAGTTGACAAAGAGAAGCCTGCCAGGATTCCCATTTCCATTTGAC
  CAGG
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_004063 unedited
  CGCGATGTCACTTCAGGGCCGGAGAGGCACTGGGGAGGGGTCACAGGGATGCCACCCGGG
  ATCTGTTCAGGAAACAGCTATGACCGCGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTT
  TTTTTTTTTTTTTTTTTTTTTTTTTCCCCCTTGATAAAAAAAAAATGTACAAAATATTTA
  ATGATTCTGTCTTGCCCCAAAAGGGAAAAACACAATTACCTAACCCTTTTGCAAAAAGGA
  AAAATGTCATGGAAAAATGAAAAATCTCTCTAATGTCTATAGCACATGAAATATCTAATT
  AGGGGGGTGCAGGGGTTCATGCCTGTTTTGGGAAACCAAGGCAGGCAAATCACTTGACGT
  CAGGAGTTCAAAACCACCCTGGCCAAATGGCGAACCCCCGTCTCTATTAAAAATACAAAA
  ATTAGCTGGGCATGGGGGGGGGTGCCTGTAAACCCAGCTACTTAGGAAGCTGAGGCAGGA
  AAATCATGTGAACCCAGGAGGCGGAGGTTGCAGTGAGCTGGGATCACACCACTGTACTCC
  AGCCTGGGCGACAGAGCAAGACTCCCCCTCAAAAAAGAAATATTTAGCAAATATTAAAGG
  ACAAGAGGGAATATCTGTTTAAAAAATTATAATGCACGTTAGATGAAAAGTAATAGGATG
  AGATGGTTGTTGCTGAAATAGCACTTGCTATATAAATTCAAACATTCCTTTTCAAATTCA
  GCTTCTCAGAGGTTTGACTTCAGATGCTTGAGCACTTTCAACATTATCTTTGCCTTTATC
  CTTCTTTATGCGGATAAACAACACTGCTAAAATAATACCAATCACCAGAGGGTGGTCAGC
  AGTATACAACTGCATGCCCCAGTGGGTATCCCAGTCTGGTGACTGCTGCGAACACTCTCC
  AACACTGCAGATGTACTGTAAGAACATGCTCAGGTGGCCGA
  
• Restriction Sites: NotI-NotI
• ACCN: NM_004063
• Insert Size: 3100 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_004063.2, NP_004054.2
• RefSeq Size: 3697 bp
• RefSeq ORF: 2499 bp
• Locus ID: 1015
• UniProt ID: Q12864
• Cytogenetics: 8q22.1
• Protein Families: Transmembrane
• Gene Summary: This gene is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. The encoded protein is cadherin-like, consisting of an extracellular region, containing 7 cadherin domains, and a transmembrane region but lacking the conserved cytoplasmic domain. The protein is a component of the gastrointestinal tract and pancreatic ducts, acting as an intestinal proton-dependent peptide transporter in the first step in oral absorption of many medically important peptide-based drugs. The protein may also play a role in the morphological organization of liver and intestine. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2009]
  Transcript Variant: This variant (1) represents the longer transcript. Both variants 1 and 2 encode the same protein.