CCR9 (NM_031200) Human Untagged Clone

CAT#: SC310478

CCR9 (untagged)-Human chemokine (C-C motif) receptor 9 (CCR9), transcript variant A

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: CCR9
• Synonyms: CC-CKR-9; CDw199; GPR-9-6; GPR28
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_031200 edited
  CTGACCCACCATGACACCCACAGACTTCACAAGCCCTATTCCTAACATGGCTGATGACTA
  TGGCTCTGAATCCACATCTTCCATGGAAGACTACGTTAACTTCAACTTCACTGACTTCTA
  CTGTGAGAAAAACAATGTCAGGCAGTTTGCGAGCCATTTCCTCCCACCCTTGTACTGGCT
  CGTGTTCATCGTGGGTGCCTTGGGCAACAGTCTTGTTATCCTTGTCTACTGGTACTGCAC
  AAGAGTGAAGACCATGACCGACATGTTCCTTTTGAATTTGGCAATTGCTGACCTCCTCTT
  TCTTGTCACTCTTCCCTTCTGGGCCATTGCTGCTGCTGACCAGTGGAAGTTCCAGACCTT
  CATGTGCAAGGTGGTCAACAGCATGTACAAGATGAACTTCTACAGCTGTGTGTTGCTGAT
  CATGTGCATCAGCGTGGACAGGTACATTGCCATTGCCCAGGCCATGAGAGCACATACTTG
  GAGGGAGAAAAGGCTTTTGTACAGCAAAATGGTTTGCTTTACCATCTGGGTATTGGCAGC
  TGCTCTCTGCATCCCAGAAATCTTATACAGCCAAATCAAGGAGGAATCCGGCATTGCTAT
  CTGCACCATGGTTTACCCTAGCGATGAGAGCACCAAACTGAAGTCAGCTGTCTTGACCCT
  GAAGGTCATTCTGGGGTTCTTCCTTCCCTTCGTGGTCATGGCTTGCTGCTATACCATCAT
  CATTCACACCCTGATACAAGCCAAGAAGTCTTCCAAGCACAAAGCCCTAAAAGTGACCAT
  CACTGTCCTGACCGTCTTTGTCTTGTCTCAGTTTCCCTACAACTGCATTTTGTTGGTGCA
  GACCATTGACGCCTATGCCATGTTCATCTCCAACTGTGCCGTTTCCACCAACATTGACAT
  CTGCTTCCAGGTCACCCAGACCATCGCCTTCTTCCACAGTTGCCTGAACCCTGTTCTCTA
  TGTTTTTGTGGGTGAGAGATTCCGCCGGGATCTCGTGAAAACCCTGAAGAACTTGGGTTG
  CATCAGCCAGGCCCAGTGGGTTTCATTTACAAGGAGAGAGGGAAGCTTGAAGCTGTCGTC
  TATGTTGCTGGAGACAACCTCAGGAGCACTCTCCCTCTGAGGGGTCTTCTCTGAGGT
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_031200 unedited
  NNNGTTCAAATTTGTATACGACTCACTATAGGCGGCCGCCAGTGTGATGGATATCTGCAG
  AATTCGGCTTGATCCTGACCCACCATGACACCCACANACTTCACAAGCCCTATTCCTAAC
  ATGGCTGATGACTATGGCTCTGAATCCACATCTTCCATGGAAGACTACGTTAACTTCAAC
  TTCACTGACTTCTACTGTGAGAAAAACAATGTCAGGCAGTTTGCGAGCCATTTCCTCCCA
  CCCTTGTACTGGCTCGTGTTCATCGTGGGTGCCTTGGGCAACAGTCTTGTTATCCTTGTC
  TACTGGTACTGCACAAGAGTGAAGACCATGACCGACATGTTCCTTTTGAATTTGGCAATT
  GCTGACCTCCTCTTTCTTGTCACTCTTCCCTTCTGGGCCATTGCTGCTGCTGACCAGTGG
  AAGTTCCAGACCTTCATGTGCAAGGTGGTCAACAGCATGTACAAGATGAACTTCTACAGC
  TGTGTGTTGCTGATCATGTGCATCAGCGTGGACAGGTACATTGCCATTGCCCAGGCCATG
  AGAGCACATACTTGGAGGGAGAAAAGGCTTTTGTACAGCAAAATGGTTTGCTTTACCATC
  TGGGTATTGGCAGCTGCTCTCTGCATCCCAGAAATCTTATACAGCCAAATCAAGGAGGAA
  TCCGGCATTGCTATCTGCACCATGGTTTACCCTAGCGATGAGAGCACCAAACTGAAGTCA
  GCTGTCTTGACNCTGAANGTCATTCTGGGGGTTCTTCCTTCCCTTCGTGGTCATGGCTTG
  CTGCTATACCATCATCATTCACACCCTGATACAGCCCAAGAAGTCTCCAAGCACAAACCC
  TAAAGTGACCTCACTGTCCTGACCGGCTTTGTCTTGCCTCAGTTTCCTACACTGCTTTTG
  GTGGGTGCAAACATTGACGCCTATGCATGTTCATCTCC
  
  3' Read Nucleotide Sequence

  >OriGene 3' genomic read for NM_031200 unedited
  GNGANGAGCACTGGGGNGGGGTCACAGGGATGCCACCCGGGCACTGTTCAGGAAACAGCT
  ATGACCGCGGCCGCAATCTAGAGTCGACAAGCTTGATATCGGTACCGAGCTCGGATCCAC
  TAGTAACGGCCGCCAGTGTGCTGGAATTCGGCTTACCTCAGAGAAGACCCCTCAGAGGGA
  GAGTGCTCCTGAGGTTGTCTCCAGCAACATAGACGACAGCTTCAAGCTTCCCTCTCTCCT
  TGTAAATGAAACCCACTGGGCCTGGCTGATGCAACCCAAGTTCTTCAGGGTTTTCACGAG
  ATCCCGGCGGAATCTCTCACCCACAAAAACATAGAGAACAGGGTTCAGGCAACTGTGGAA
  GAAGGCGATGGTCTGGGTGACCTGGAAGCAGATGTCAATGTTGGTGGAAACGGCACAGTT
  GGAGATGAACATGGCATAGGCGTCAATGGTCTGCACCAACAAAATGCAGTTGTAGGGAAA
  CTGAGACAAGACAAAGACGGTCAGGACAGTGATGGTCACTTTTAGGGCTTTGTGCTTGGA
  AGACTTCTTGGCTTGTATCAGGGTGTGAATGATGATGGTATAGCAGCAAGCCATGACCAC
  GAAGGGAAGGAAGAACCCCAGAATGACCTTCAGGGTCAAGACAGCTGACTTCAGTTTGGT
  GCTCTCATCGCTAGGGTAAACCATGGTGCAGATAGCAATGCCGGATTCCTCCTTGATTTG
  GCTGTATAAGATTTCTGGGATGCAGAGAGCAGCTGCCAATACCCAGATGGTAAAGCAAAC
  CATTTTGCTGTACAAAAGCCTTTTCTCCCTCCAGTATGTGCTCTCATGGGCCGGGCCATG
  GCAATGTACCTGTCCACGCG
  
• Restriction Sites: Please inquire
• ACCN: NM_031200
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_031200.1, NP_112477.1
• RefSeq Size: 2544 bp
• RefSeq ORF: 1110 bp
• Locus ID: 10803
• UniProt ID: P51686
• Cytogenetics: 3p21.31
• Protein Families: Druggable Genome, GPCR, Transmembrane
• Protein Pathways: Chemokine signaling pathway, Cytokine-cytokine receptor interaction
• Gene Summary: The protein encoded by this gene is a G protein-coupled receptor with seven transmembrane domains that belongs to the beta chemokine receptor family. Chemokines and their receptors are key regulators of thymocyte migration and maturation in normal and inflammation conditions. This gene is differentially expressed in T lymphocytes of the small intestine and colon, and its interaction with chemokine 25 contributes to intestinal intra-epithelial lymphocyte homing to the small intestine. This suggests a role for this gene in directing immune responses to different segments of the gastrointestinal tract. This gene and its exclusive ligand, chemokine 25, are overexpressed in a variety of malignant tumors and are closely associated with tumor proliferation, apoptosis, invasion, migration and drug resistance. This gene maps to the chemokine receptor gene cluster. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2020]
  Transcript Variant: This variant (A) encodes the longer isoform (A).