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BPTF (NM_182641) Human Untagged Clone
CAT#: SC307471
BPTF (untagged)-Human bromodomain PHD finger transcription factor (BPTF), transcript variant 1
"NM_182641" in other vectors (2)
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Frequently bought together (2)
Other products for "BPTF"
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Symbol | BPTF |
| Synonyms | FAC1; FALZ; NEDDFL; NURF301 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>SC307471 representing NM_182641.
Blue=Insert sequence Red=Cloning site Green=Tag(s) GCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTG GATCCGGTACCGAGGAGATCTGCCGCCGCGATCGCC ATGAGGGGCCGGCGGGGCAGGCCGCCCAAGCAGCCCGCGGCTCCCGCTGCGGAGCGCTGCGCCCCGGCC CCGCCGCCACCGCCGCCGCCGCCCACGTCCGGACCCATCGGGGGGCTCCGCTCGCGGCACCGCGGCAGC AGCCGGGGCAGGTGGGCCGCCGCCCAGGCTGAGGTGGCGCCCAAGACGCGGCTGAGCTCGCCCAGGGGG GGCAGCAGTAGCCGGAGGAAGCCGCCGCCGCCGCCGCCGGCCCCCCCCAGCACCAGCGCCCCGGGCCGG GGGGGGCGAGGAGGCGGGGGCGGCAGGACGGGGGGCGGGGGCGGCGGCGGCCACCTGGCCCGGACCACC GCGGCCCGGAGGGCCGTCAACAAAGTGGTGTACGATGACCACGAGAGCGAGGAGGAGGAGGAAGAGGAG GACATGGTCTCCGAGGAGGAGGAGGAGGAGGACGGCGACGCCGAGGAGACCCAGGATTCTGAGGACGAC GAGGAGGATGAGATGGAAGAGGACGACGATGACTCCGATTATCCGGAGGAGATGGAAGACGACGACGAC GACGCCAGTTACTGCACGGAAAGCAGCTTCAGGAGCCATAGTACCTACAGCAGCACTCCAGGTAGGCGA AAACCAAGAGTACATCGGCCTCGTTCTCCTATATTGGAAGAAAAAGACATCCCGCCCCTTGAATTTCCC AAGTCCTCTGAGGATTTAATGGTGCCTAATGAGCATATAATGAATGTCATTGCCATTTACGAGGTACTG CGGAACTTTGGCACTGTTTTGAGATTATCTCCTTTTCGCTTTGAGGACTTTTGTGCAGCTCTGGTGAGC CAAGAGCAGTGCACACTCATGGCAGAGATGCATGTTGTGCTTTTGAAAGCAGTTCTGCGTGAAGAAGAC ACTTCCAATACTACCTTTGGACCTGCTGATCTGAAAGATAGCGTTAATTCCACACTGTATTTCATAGAT GGGATGACGTGGCCAGAGGTGCTGCGGGTGTACTGTGAGAGTGATAAGGAGTACCATCACGTTCTTCCT TACCAAGAGGCAGAGGACTACCCATATGGACCAGTAGAGAACAAGATCAAAGTTCTACAGTTTCTAGTC GATCAGTTTCTTACAACAAATATTGCTCGAGAGGAATTGATGTCTGAAGGGGTGATACAGTATGATGAC CATTGTAGGGTTTGTCACAAACTTGGGGATTTGCTTTGCTGTGAGACATGTTCAGCAGTATACCATTTG GAATGTGTGAAGCCACCTCTTGAGGAGGTGCCAGAGGACGAGTGGCAGTGTGAAGTCTGTGTAGCACAC AAGGTGCCTGGTGTGACTGACTGTGTTGCTGAAATCCAAAAAAATAAACCATATATTCGACATGAACCT ATTGGATATGATAGAAGTCGGAGGAAATACTGGTTCTTGAACCGAAGACTCATAATAGAAGAAGATACA GAAAATGAAAATGAAAAGAAAATTTGGTATTACAGCACAAAGGTCCAACTTGCAGAATTAATTGACTGT CTAGACAAAGATTATTGGGAAGCAGAACTCTGCAAAATTCTAGAAGAAATGCGTGAAGAAATCCACCGA CACATGGACATAACTGAAGACCTGACCAATAAGGCTCGGGGCAGTAACAAATCCTTTCTGGCGGCAGCT AATGAAGAAATTTTGGAATCCATAAGAGCCAAAAAGGGAGACATTGATAATGTTAAAAGCCCAGAAGAA ACAGAAAAAGACAAGAATGAGACTGAGAATGACTCTAAAGATGCTGAGAAAAACAGAGAAGAATTTGAA GACCAGTCCCTTGAAAAAGACAGTGACGACAAAACACCAGATGATGACCCTGAGCAAGGAAAATCTGAG GTAGGTGATTTCAAATCGGAGAAGTCCAACGGGGAGCTAAGTGAATCTCCTGGAGCTGGAAAAGGAGCA TCTGGCTCAACTCGAATCATCACCAGATTGCGGAATCCAGATAGCAAACTTAGTCAGCTGAAGAGCCAG CAGGTGGCAGCCGCTGCACATGAAGCAAATAAATTATTTAAGGAGGGCAAAGAGGTACTGGTAGTTAAC TCTCAAGGAGAAATTTCACGGTTGAGCACCAAAAAGGAAGTGATCATGAAAGGAAATATCAACAATTAT TTTAAATTGGGTCAAGAAGGGAAGTATCGCGTCTACCACAATCAATACTCCACCAATTCATTTGCTTTG AATAAGCACCAGCACAGAGAAGACCATGATAAGAGAAGGCATCTTGCACATAAGTTCTGTCTGACTCCA GCAGGAGAGTTCAAATGGAACGGTTCTGTCCATGGGTCCAAAGTTCTTACCATATCTACTCTGAGACTG ACTATCACCCAATTAGAAAACAACATCCCTTCATCCTTTCTTCATCCCAACTGGGCATCACATAGGGCA AATTGGATCAAGGCAGTTCAGATGTGTAGCAAACCCAGAGAATTTGCATTGGCTTTAGCCATTTTGGAG TGTGCAGTTAAACCAGTTGTGATGCTACCAATATGGCGAGAATCTTTAGGACATACCAGGTTACACCGG ATGACATCAATTGAAAGAGAAGAAAAGGAGAAAGTCAAAAAAAAAGAGAAGAAACAGGAAGAAGAAGAA ACGATGCAGCAAGCGACATGGGTAAAATACACATTTCCAGTTAAGCATCAGGTTTGGAAACAAAAAGGT GAAGAGTACAGAGTGACAGGATATGGTGGTTGGAGCTGGATTAGTAAAACTCATGTTTATAGGTTTGTT CCTAAATTGCCAGGCAATACTAATGTGAATTACAGAAAGTCGTTAGAAGGAACCAAAAATAATATGGAT GAAAATATGGATGAGTCAGATAAAAGAAAATGTTCACGAAGTCCAAAAAAAATAAAAATAGAGCCTGAT TCTGAAAAAGATGAGGTAAAAGGTTCAGATGCTGCAAAAGGAGCAGACCAAAATGAAATGGATATCTCA AAGATTACTGAGAAGAAGGACCAAGATGTGAAGGAGCTCTTAGATTCTGACAGTGATAAACCCTGCAAG GAAGAACCAATGGAAGTAGACGATGACATGAAAACAGAGTCACATGTAAATTGTCAGGAGAGTTCTCAA GTAGATGTGGTCAATGTTAGTGAGGGTTTTCATCTAAGGACTAGTTACAAAAAGAAAACAAAATCATCC AAACTAGATGGACTTCTTGAAAGGAGAATTAAACAGTTTACACTGGAAGAAAAACAGCGACTCGAAAAA ATCAAGTTGGAGGGTGGAATTAAGGGTATAGGAAAGACTTCTACAAATTCTTCAAAAAATCTCTCTGAA TCACCAGTAATAACGAAAGCAAAAGAAGGGTGTCAGAGTGACTCGATGAGACAAGAACAGAGCCCAAAT GCAAATAATGATCAACCTGAGGACTTGATTCAGGGATGTTCAGAAAGTGATTCCTCAGTTCTTAGAATG AGTGATCCTAGTCATACCACAAACAAACTTTATCCAAAAGATCGAGTGTTAGATGATGTCTCCATTCGG AGCCCAGAAACAAAATGTCCGAAACAAAATTCCATTGAAAATGACATAGAAGAAAAAGTCTCTGACCTT GCCAGTAGAGGCCAGGAACCCAGTAAGAGTAAAACAAAAGGAAATGATTTTTTCATCGATGACTCTAAA CTAGCCAGTGCAGATGATATTGGTACTTTGATCTGTAAGAACAAAAAACCGCTCATACAGGAGGAAAGT GACACCATTGTTTCTTCTTCCAAGAGTGCTTTACATTCATCAGTGCCTAAAAGTACCAATGACAGAGAT GCCACACCTCTGTCAAGAGCAATGGACTTTGAAGGAAAACTGGGATGTGACTCTGAATCTAATAGCACT TTGGAAAATAGTTCTGATACCGTGTCTATTCAGGATAGCAGTGAAGAAGATATGATTGTTCAGAATAGC AATGAAAGCATTTCTGAACAGTTCAGAACTCGAGAACAAGATGTTGAAGTCTTGGAGCCGTTAAAGTGT GAGTTGGTTTCTGGTGAGTCCACTGGAAACTGTGAGGACAGGCTGCCGGTCAAGGGGACTGAAGCAAAT GGTAAAAAACCAAGTCAGCAGAAGAAATTAGAGGAGAGACCAGTTAATAAATGTAGTGATCAAATAAAG CTAAAAAATACCACTGACAAAAAGAATAATGAAAATCGAGAGTCTGAAAAGAAAGGACAGAGAACAAGT ACATTTCAAATAAATGGAAAAGATAATAAACCCAAAATATATTTGAAAGGTGAATGCTTGAAAGAAATT TCTGAGAGTAGAGTAGTAAGTGGTAATGTTGAACCAAAGGTTAATAATATAAATAAAATAATCCCTGAG AATGATATTAAATCATTGACTGTTAAAGAATCTGCTATAAGGCCATTCATTAATGGTGATGTCATCATG GAAGATTTTAATGAAAGAAACAGCTCCGAAACAAAATCGCATTTGCTGAGTTCTTCAGATGCTGAAGGT AACTACCGAGATAGCCTTGAGACCCTGCCATCAACCAAAGAGTCTGACAGTACACAGACGACCACACCC TCAGCATCTTGTCCAGAAAGCAATTCAGTTAATCAGGTAGAAGATATGGAAATAGAAACCTCAGAAGTT AAGAAAGTTACTTCATCACCTATTACTTCTGAAGAGGAATCTAATCTCAGTAATGACTTTATTGATGAA AATGGTCTGCCCATCAACAAAAATGAAAATGTCAATGGAGAATCTAAAAGAAAAACCGTCATCACAGAA GTCACCACGATGACCTCCACAGTGGCCACAGAATCAAAAACTGTGATCAAGGTAGAAAAAGGCGATAAG CAAACTGTGGTTTCTTCCACAGAAAATTGTGCAAAATCCACTGTCACAACCACCACTACAACAGTGACC AAGCTTTCCACACCCTCCACAGGCGGCAGTGTGGACATCATCTCTGTAAAGGAGCAGAGCAAAACCGTG GTCACCACGACAGTGACAGACTCCCTGACCACCACGGGAGGCACACTGGTTACATCTATGACTGTGAGC AAAGAGTATTCCACACGAGACAAAGTGAAACTGATGAAATTTTCAAGACCAAAGAAGACTCGTTCAGGT ACAGCTCTGCCATCCTATAGAAAATTTGTTACCAAGAGCAGCAAGAAGAGCATTTTTGTTTTGCCTAAT GATGACTTAAAAAAGTTGGCCCGAAAAGGAGGAATCCGAGAGGTCCCTTATTTTAATTACAATGCAAAA CCTGCTTTGGATATATGGCCATATCCTTCTCCTAGACCGACCTTTGGCATCACTTGGAGGTATAGACTT CAGACAGTAAAGTCCTTAGCTGGAGTGAGCCTGATGTTACGGTTACTGTGGGCAAGTTTGAGATGGGAT GATATGGCGGCCAAGGCTCCTCCAGGAGGAGGGACTACACGGACAGAAACATCCGAAACTGAAATCACA ACAACAGAAATAATTAAGAGGAGAGATGTTGGTCCTTATGGCATTCGATCTGAATATTGTATCAGGAAA ATCATTTGTCCCATTGGAGTTCCAGAAACACCAAAAGAAACGCCTACACCTCAGAGGAAAGGCCTTCGA TCAAGTGCACTGCGGCCAAAGAGACCAGAAACGCCCAAGCAAACTGGCCCTGTTATTATTGAAACCTGG GTAGCAGAAGAAGAACTGGAATTGTGGGAGATCAGGGCATTTGCTGAGAGAGTGGAGAAAGAAAAGGCA CAAGCAGTTGAGCAACAGGCTAAGAAACGACTGGAGCAGCAGAAGCCGACAGTGATTGCAACTTCCACT ACTTCCCCAACAAGCAGTACAACCAGCACCATCTCTCCAGCACAGAAGGTTATGGTGGCCCCCATAAGT GGCTCAGTTACAACTGGAACCAAAATGGTACTAACTACTAAAGTTGGATCTCCAGCTACAGTAACATTC CAACAAAACAAGAACTTTCATCAAACCTTTGCTACATGGGTTAAGCAAGGCCAGTCAAATTCAGGCGTT GTTCAAGTACAGCAGAAAGTCCTGGGTATCATTCCATCAAGTACAGGTACCAGTCAGCAAACCTTTACT TCATTCCAGCCCAGGACAGCAACAGTCACAATTAGGCCCAATACCTCAGGCTCTGGAGGAACCACAAGC AATTCACAAGTAATCACAGGGCCTCAGATTCGCCCTGGTATGACCGTGATTAGAACACCACTCCAACAG TCAACACTAGGAAAGGCAATTATTCGAACACCTGTGATGGTACAGCCAGGTGCTCCTCAGCAAGTGATG ACTCAAATCATCAGGGGGCAGCCTGTCTCCACTGCAGTCTCCGCCCCTAACACGGTTTCCTCAACACCT GGGCAGAAAAGCTTAACTTCAGCAACGTCCACTTCAAATATACAGTCTTCAGCCTCACAACCCCCTCGC CCCCAACAAGGACAAGTGAAGCTCACCATGGCTCAACTTACTCAGTTAACACAGGGCCACGGTGGCAAT CAAGGTTTGACAGTAGTAATTCAAGGACAAGGTCAAACTACTGGACAGTTGCAGTTGATACCTCAAGGG GTGACTGTACTCCCAGGCCCAGGCCAGCAGCTAATGCAAGCTGCAATGCCAAATGGTACTGTTCAGCGA TTCCTCTTTACCCCATTGGCAACAACAGCCACCACAGCCAGCACCACCACCACCACTGTTTCCACGACA GCAGCAGGTACAGGTGAACAAAGGCAGAGTAAACTGTCACCCCAGATGCAGGTACATCAAGACAAAACC CTGCCACCAGCTCAGTCATCAAGTGTGGGTCCAGCAGAAGCCCAGCCACAGACTGCTCAGCCTTCAGCT CAGCCCCAGCCCCAAACCCAGCCCCAGTCCCCAGCTCAGCCTGAAGTTCAGACTCAGCCTGAAGTTCAG ACCCAAACAACTGTTTCATCCCATGTCCCTTCTGAAGCACAACCCACCCACGCACAGTCATCCAAGCCC CAAGTTGCAGCACAGTCTCAGCCTCAAAGTAATGTCCAAGGACAGTCTCCTGTTCGTGTCCAAAGTCCA TCACAGACTCGAATACGTCCATCAACTCCATCCCAACTGTCTCCTGGACAACAATCCCAGGTTCAGACT ACAACCTCACAACCGATTCCAATTCAACCACATACATCTCTTCAGATACCTTCCCAAGGCCAGCCACAG TCACAACCCCAGGTACAGTCTTCAACTCAAACTCTTTCATCAGGACAAACTTTAAATCAAGTTACTGTT TCATCCCCATCCCGTCCTCAGCTACAAATACAGCAGCCACAGCCCCAAGTCATTGCTGTGCCTCAGCTG CAACAACAAGTCCAGGTTCTCTCTCAGATCCAGTCACAGGTTGTGGCTCAGATACAGGCTCAGCAAAGT GGTGTGCCCCAGCAAATCAAACTCCAGTTACCTATCCAAATTCAGCAAAGCAGTGCTGTGCAGACTCAC CAGATTCAGAATGTGGTTACAGTGCAGGCAGCCAGTGTGCAAGAGCAGTTGCAAAGGGTTCAGCAACTC AGGGATCAGCAGCAAAAGAAGAAACAGCAACAGATAGAAATTAAGCGTGAACACACCCTCCAAGCTTCT AATCAAAGTGAAATCATTCAGAAACAGGTGGTGATGAAGCATAATGCTGTAATAGAACATTTAAAACAG AAAAAGAGCATGACTCCAGCTGAAAGAGAAGAGAATCAAAGAATGATTGTCTGTAACCAGGTGATGAAG TATATTTTGGATAAGATAGATAAAGAAGAAAAACAGGCAGCAAAAAAACGGAAGCGTGAAGAGAGTGTG GAGCAGAAACGTAGCAAGCAGAATGCCACTAAGCTGTCAGCTCTGCTCTTCAAGCACAAAGAGCAGCTC AGAGCCGAGATCCTGAAGAAGAGAGCACTCCTGGACAAGGATCTGCAAATTGAAGTGCAGGAAGAGCTG AAGAGAGACCTGAAAATTAAGAAAGAAAAAGACCTGATGCAGTTGGCTCAGGCCACAGCAGTAGCTGCA CCCTGCCCCCCAGTGACACCAGCTCCTCCAGCCCCTCCAGCCCCTCCACCTTCACCTCCCCCTCCACCT GCTGTGCAACACACAGGCCTTCTGTCCACGCCCACCTTACCTGCTGCTTCCCAGAAGAGGAAGCGGGAA GAGGAAAAAGACTCCAGCTCAAAGTCCAAGAAAAAGAAAATGATCTCTACTACCTCAAAGGAAACTAAG AAGGACACAAAGCTTTACTGTATCTGTAAAACGCCTTATGATGAATCTAAATTTTATATTGGCTGTGAT CGGTGTCAGAATTGGTACCATGGGCGCTGCGTTGGCATCTTGCAAAGTGAGGCAGAGCTCATTGATGAG TATGTCTGTCCACAGTGCCAGTCAACAGAGGATGCCATGACAGTGCTCACGCCACTAACAGAGAAGGAT TATGAGGGGTTGAAGAGGGTGCTCCGTTCCTTACAGGCCCATAAGATGGCCTGGCCTTTCCTTGAACCA GTAGACCCTAATGATGCACCAGATTATTATGGTGTTATTAAGGAACCTATGGACCTTGCCACCATGGAA GAAAGAGTACAAAGACGATATTATGAAAAGCTGACGGAATTTGTGGCAGATATGACCAAAATTTTTGAT AACTGTCGTTACTACAATCCAAGTGACTCCCCATTTTACCAGTGTGCAGAAGTTCTCGAATCATTCTTT GTACAGAAATTGAAAGGCTTCAAAGCTAGCAGGTCTCATAACAACAAACTGCAGTCTACAGCTTCTTAA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGAT TACAAGGATGACGACGATAAGGTTTAAACGGCCGGC |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_182641 |
| Insert Size | 8763 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_182641.3 |
| RefSeq Size | 10914 bp |
| RefSeq ORF | 8763 bp |
| Locus ID | 2186 |
| UniProt ID | Q12830 |
| Cytogenetics | 17q24.2 |
| Protein Families | Druggable Genome |
| MW | 325.1 kDa |
| Gene Summary | This gene was identified by the reactivity of its encoded protein to a monoclonal antibody prepared against brain homogenates from patients with Alzheimer's disease. Analysis of the original protein (fetal Alz-50 reactive clone 1, or FAC1), identified as an 810 aa protein containing a DNA-binding domain and a zinc finger motif, suggested it might play a role in the regulation of transcription. High levels of FAC1 were detected in fetal brain and in patients with neurodegenerative diseases. The protein encoded by this gene is actually much larger than originally thought, and it also contains a C-terminal bromodomain characteristic of proteins that regulate transcription during proliferation. The encoded protein is highly similar to the largest subunit of the Drosophila NURF (nucleosome remodeling factor) complex. In Drosophila, the NURF complex, which catalyzes nucleosome sliding on DNA and interacts with sequence-specific transcription factors, is necessary for the chromatin remodeling required for transcription. Two alternative transcripts encoding different isoforms have been described completely. [provided by RefSeq, Jul 2008] Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). |
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