Keratin 80 (KRT80) (NM_182507) Human Untagged Clone

CAT#: SC307410

KRT80 (untagged)-Human keratin 80 (KRT80), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: Keratin 80
• Synonyms: KB20
• Vector: pCMV6-XL6
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_182507 edited
  CCCAGCTGTGACCAGAGCAACCAGAGCCTGCCACCCGACGCAACCCCAGGCTCACTCGCT
  CACCCCCCTGGGCCCTCCTGCTTCCGGCCGGGGGCACCATGGCCTGCCGCTCCTGCGTGG
  TTGGCTTCAGCAGCCTCAGCAGCTGTGAGGTGACCCCGGTGGGCAGCCCCCGGCCTGGAA
  CCTCAGGATGGGACAGCTGCAGGGCCCCCGGGCCGGGCTTCAGCTCCCGCAGCCTCACAG
  GCTGCTGGTCGGCTGGCACTATCTCCAAGGTGACTGTGAACCCCGGCCTGCTGGTGCCCC
  TGGATGTCAAGTTGGACCCCGCTGTTCAGCAGCTGAAGAACCAGGAGAAGGAGGAGATGA
  AGGCCCTCAATGATAAATTTGCCTCCCTAATTGGCAAGGTGCAAGCCCTGGAACAGCGCA
  ACCAGCTGCTGGAGACACGCTGGAGCTTCCTGCAGGGCCAGGACTCAGCCATCTTCGACC
  TCGGGCATCTCTATGAGGAATATCAGGGCCGGCTGCAGGAGGAACTGCGCAAAGTGAGCC
  AGGAGCGGGGGCAGCTGGAGGCCAACCTGCTGCAGGTGCTGGAGAAGGTTGAGGAGTTTC
  GAATCAGGTATGAGGATGAGATCTCCAAGCGCACAGACATGGAGTTCACCTTTGTTCAGC
  TGAAGAAGGACCTGGATGCAGAGTGTCTTCATCGGACTGAACTGGAAACCAAGTTAAAAA
  GCCTGGAGAGCTTCGTGGAGTTGATGAAAACCATCTATGAGCAGGAGCTGAAGGACCTGG
  CAGCACAGGTGAAGGATGTGTCGGTGACCGTCGGCATGGACAGCCGCTGCCACATCGACC
  TGAGCGGCATCGTGGAGGAGGTGAAGGCCCAGTATGACGCCGTCGCGGCTCGCAGCCTGG
  AGGAGGCCGAGGCATACTCTCGGAGCCAGCTGGAGGAGCAGGCCGCCCGCTCGGCCGAGT
  ATGGGAGCAGCCTCCAGAGCAGCCGCAGCGAGATCGCGGATCTCAATGTGCGCATCCAGA
  AGCTGCGGTCCCAGATCCTCTCTGTCAAGAGCCATTGCCTGAAACTGGAGGAGAACATCA
  AGACAGCTGAGGAGCAGGGTGAGCTGGCCTTCCAGGATGCCAAGACCAAGCTGGCCCAGC
  TGGAGGCCGCCCTGCAGCAGGCCAAGCAGGACATGGCGCGGCAGCTGCGCAAGTACCAGG
  AGCTGATGAATGTCAAGCTGGCCCTGGACATCGAGATCGCCACCTACAGG:AAGCTGGTG
  GAGGGCGAGGAGGGCAGGATGGACTCGCCCTCAGCCACTGTGGTCAGCGCTGTGCAGTCC
  AGGTGCAAAACCGCTGCCTCCAGATCAGGCCTCTCCAAGGCCCCCTCCCGAAAGAAGAAG
  GGCAGCAAAGGCCCCGTGATCAAAATCACCGAAATGTCAGAGAAGTACTTCTCGCAGGAG
  TCGGAGGTCTCAGAGTAAGGCGGCTGGACCCCAGGAACCCCAGGGCACTCCACTGCAGCA
  GGAGGGACTTAAGCTAGACTCAAGAAAGCAGCTTGGAGCCTCTAGGTTGAGAAGAGAGGC
  AAAACCTGATATTGAACTGAGAGAGGGGTTCAAAACTGACTGTGTTTTGTGGGCTGCCAG
  GGTGGGAGAGGAGCATCACCAGCTCCTCAGAGCCACTCCGCTCCATATCAGTATCTCACA
  GTCCCATCCTTCCAACCTTCTGGCCAGAGGTTTTCCTGATGGGTGAGTCGGAATTAGGGG
  TCAGTTTTGTCTCCACCTCCTCGCTCCTCTGAGGCTCCTCCTCCAGCATCAGGCTCTGCC
  AAGGCCCCTCTGACTCTTGCCCAATCCTTGACCTTGACTCCTATCTCAAGCCTTGCCTTG
  TCTCTGCCTCGGAACTGGGACTGGGACTGGCTCATCCACCTATGTGCGGGAGCCGAGGAG
  GACGGCGTGGGCCCTGTCCTGTATCTGG
  
• Restriction Sites: Please inquire
• ACCN: NM_182507
• Insert Size: 2000 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: The ORF of this clone has been fully sequenced and found to be a perfect match to NM_182507.1.
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_182507.1, NP_872313.1
• RefSeq Size: 3411 bp
• RefSeq ORF: 1464 bp
• Locus ID: 144501
• UniProt ID: Q6KB66
• Cytogenetics: 12q13.13
• Gene Summary: Keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into epithelial keratins and hair keratins. This gene's expression profile shows that it encodes a type II epithelial keratin, although structurally the encoded protein is more like a type II hair keratin. This protein is involved in cell differentiation, localizing near desmosomal plaques in earlier stages of differentiation but then dispersing throughout the cytoplasm in terminally differentiating cells. The type II keratins are clustered in a region of chromosome 12q13. Two transcript variants encoding two different fully functional isoforms have been found for this gene.[provided by RefSeq, Oct 2010]
  Transcript Variant: This variant (1) encodes the longer isoform (K80, also known as a).