IL21 (NM_021803) Human Untagged Clone
IL21 (untagged)-Human interleukin 21 (IL21), transcript variant 1
|Product Name||IL21 (NM_021803) Human Untagged Clone|
|Synonyms||CVID11; IL-21; Za11|
Fully Sequenced ORF
>OriGene sequence for NM_021803 edited
|ORF Size||489 bp|
|OTI Disclaimer||Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).|
|OTI Annotation||This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA|
|Product Components||The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.|
|Protein Families||Secreted Protein, Druggable Genome|
|Protein Pathways||Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway|
|Gene Summary||This gene encodes a member of the common-gamma chain family of cytokines with immunoregulatory activity. The encoded protein plays a role in both the innate and adaptive immune responses by inducing the differentiation, proliferation and activity of multiple target cells including macrophages, natural killer cells, B cells and cytotoxic T cells. Dysregulation of this gene plays a role in multiple immune-mediated diseases including lupus, psoriasis and chronic inflammatory diseases. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011].
Transcript Variant: This variant (1) encodes the longer isoform (1).
|cDNA Clone Resources|