FGF4 (NM_002007) Human Untagged Clone
FGF4 (untagged)-Human fibroblast growth factor 4 (FGF4)
|Product Name||FGF4 (NM_002007) Human Untagged Clone|
|Type||Human Untagged Clone|
|Synonyms||FGF-4; HBGF-4; HST; HST-1; HSTF-1; HSTF1; K-FGF; KFGF|
|E. coli Selection||Ampicillin (100 ug/mL)|
>OriGene sequence for NM_002007 edited
|Restriction Sites||Please inquire|
|Insert Size||600 bp|
|OTI Disclaimer||Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).|
|OTI Annotation||The open reading frame of this TrueClone was fully sequenced and found to be a perfect match to the protein associated to this reference.|
|Product Components||The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.|
|Reconstitution||1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
|RefSeq Size||1219 bp|
|RefSeq ORF||621 bp|
|Protein Families||Adult stem cells, Druggable Genome, Embryonic stem cells, ES Cell Differentiation/IPS, Induced pluripotent stem cells, Secreted Protein, Stem cell relevant signaling - Wnt Signaling pathway, Transmembrane|
|Protein Pathways||MAPK signaling pathway, Melanoma, Pathways in cancer, Regulation of actin cytoskeleton|
|Gene Summary||The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene was identified by its oncogenic transforming activity. This gene and FGF3, another oncogenic growth factor, are located closely on chromosome 11. Co-amplification of both genes was found in various kinds of human tumors. Studies on the mouse homolog suggested a function in bone morphogenesis and limb development through the sonic hedgehog (SHH) signaling pathway. [provided by RefSeq, Jul 2008]|
|The use of this cDNA Clones has been cited in the following citations:|
Identification of Site-Specific Degradation in Bacterially Expressed Human Fibroblast Growth Factor 4 and Generation of an Aminoterminally Truncated, Stable Form
,Sugawara, S;Ito, T;Sato, S;Sato, Y;Kasuga, K;Kojima, I;Kobayashi, M;,
Appl Biochem Biotechnol. 2013 Sep 26
,PubMed ID 24068478
|cDNA Clone Resources|
|RC217058||FGF4 (Myc-DDK-tagged)-Human fibroblast growth factor 4 (FGF4)||
|RG217058||FGF4 (GFP-tagged) - Human fibroblast growth factor 4 (FGF4)||
|RC217058L1||Lenti ORF clone of Human fibroblast growth factor 4 (FGF4), Myc-DDK-tagged||
|RC217058L2||Lenti ORF clone of Human fibroblast growth factor 4 (FGF4), mGFP tagged||
|RC217058L3||Lenti ORF clone of Human fibroblast growth factor 4 (FGF4), Myc-DDK-tagged||
|RC217058L4||Lenti ORF clone of Human fibroblast growth factor 4 (FGF4), mGFP tagged||