Flt3 ligand(FLT3LG) (NM_001459) Human Untagged Clone
FLT3LG (untagged)-Human fms-related tyrosine kinase 3 ligand (FLT3LG), transcript variant 3
|Product Name||Flt3 ligand(FLT3LG) (NM_001459) Human Untagged Clone|
Fully Sequenced ORF
>OriGene sequence for NM_001459 edited
|ORF Size||708 bp|
|OTI Disclaimer||Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).|
|OTI Annotation||The ORF of this clone has been fully sequenced and found to be a perfect match to NM_001459.2.|
|Product Components||The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.|
|Protein Families||Secreted Protein, ES Cell Differentiation/IPS, Transmembrane, Druggable Genome|
|Protein Pathways||Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, Pathways in cancer|
|Gene Summary||Dendritic cells (DCs) provide the key link between innate and adaptive immunity by recognizing pathogens and priming pathogen-specific immune responses. FLT3LG controls the development of DCs and is particularly important for plasmacytoid DCs and CD8 (see MIM 186910)-positive classical DCs and their CD103 (ITGAE; MIM 604682)-positive tissue counterparts (summary by Sathaliyawala et al., 2010 [PubMed 20933441]).[supplied by OMIM, Jan 2011].
Transcript Variant: This variant (3) differs in the 5' UTR, compared to variant 1. Variants 1, 2, and 3 encode the same isoform (1).
|cDNA Clone Resources|
Related Products (1)
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