CD1 (CD1D) (NM_001766) Human Untagged Clone

SKU SC128240

CD1D (untagged)-Human CD1d molecule (CD1D)

Product Data

• Type: Human Untagged Clone
• Target Symbol: CD1
• Synonyms: CD1A; R3; R3G1
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF sequence for NM_001766 edited; ATGGGGTGCCTGCTGTTTCTGCTGCTCTGGGCGCTCCTCCAGGCTTGGGGAAGCGCTGAA; GTCCCGCAAAGGCTTTTCCCCCTCCGCTGCCTCCAGATCTCGTCCTTCGCCAATAGCAGC; TGGACGCGCACCGACGGCTTGGCGTGGCTGGGGGAGCTGCAGACGCACAGCTGGAGCAAC; GACTCGGACACCGTCCGCTCTCTGAAGCCTTGGTCCCAGGGCACGTTCAGCGACCAGCAG; TGGGAGACGCTGCAGCATATATTTCGGGTTTATCGAAGCAGCTTCACCAGGGACGTGAAG; GAATTCGCCAAAATGCTACGCTTATCCTATCCCTTGGAGCTCCAGGTGTCCGCTGGCTGT; GAGGTGCACCCTGGGAACGCCTCAAATAACTTCTTCCATGTAGCATTTCAAGGAAAAGAT; ATCCTGAGTTTCCAAGGAACTTCTTGGGAGCCAACCCAAGAGGCCCCACTTTGGGTAAAC; TTGGCCATTCAAGTGCTCAACCAGGACAAGTGGACGAGGGAAACAGTGCAGTGGCTCCTT; AATGGCACCTGCCCCCAATTTGTCAGTGGCCTCCTTGAGTCAGGGAAGTCGGAACTGAAG; AAGCAAGTGAAGCCCAAGGCCTGGCTGTCCCGTGGCCCCAGTCCTGGCCCTGGCCGTCTG; CTGCTGGTGTGCCATGTCTCAGGATTCTACCCAAAGCCTGTATGGGTGAAGTGGATGCGG; GGTGAGCAGGAGCAGCAGGGCACTCAGCCAGGGGACATCCTGCCCAATGCTGACGAGACA; TGGTATCTCCGAGCAACCCTGGATGTGGTGGCTGGGGAGGCAGCTGGCCTGTCCTGTCGG; GTGAAGCACAGCAGTCTAGAGGGCCAGGACATCGTCCTCTACTGGGGTGGGAGCTACACC; TCCATGGGCTTGATTGCCTTGGCAGTCCTGGCGTGCTTGCTGTTCCTCCTCATTGTGGGC; TTTACCTCCCGGTTTAAGAGGCAAACTTCCTATCAGGGCGTCCTGTGA;
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_001766 unedited; NTTTGGGGAGTCAAAATTTGTATACGACTCACTATAGGGCGGCCGCGAATTCGCACGAGG; GTGAGGTGATGTCAAAAGGTAGACACCAGGGCTAGAGGGCGCATAATCTTGCAGGCCGTG; CTAATGATTTTGTTTTCTACCCAAGAATGCTACTTCAGGAGATCAGTCAAAAGGTTAGGG; TGATGGTGACGGTGGAAATATAGAAAAAGGAATTTATTCAAGAGGTATTCAAAAAGAAGT; GAAATAGAGATGAGTTGGAGATAGATTGGATAAAAAGAGTGAGGGAGAGGGAGGTGTCAG; GCTGCAGCCCAGGTTCTGAGTTGCCAAAGAGGAGTCTTTTCCTCCAGGAAATTGAGACAC; GCCGGTTGTGAAACCTACTGAAGTGAGCGGCGGCGCCAGGATTCCTGGGACCCCGACCTC; TTTGCAGCTCGCACAGCTAAGGGCGAGGGCGCCCTTCGGCAGAAGCAGCAAACCGCCGGC; AAGCCCAGCGAGGAGGGCTGCCGGGGTCTGGGCTTGGGAATTGGCTGGCACCCAGCGAAN; AGGGACGTGAGCTGAGCGGGCGGGGAAGAGAGTGCGCAGGTCAGAAGGCGGCGCGCAGCG; GCGCTCCGCGAGGTCCCCACGCCCGGCGATATGGGGTGCCTGCTGTTTCTGCTGCTCTGG; GCGCTCCTCCAGGCTTGGGGAAGCGCTGAAGTCCCGCAAAGGCTTTTCCCCCTNCGCTGC; CTNCAGATCTCGTCCTTTGGCCATAGCAGCTGGACGCGCACCGACGCTTGGCCGTGCTGG; GGAAGCTGCANACGCACAGCTGGAGCACGACTCGGACACCGTCCGGTCTCTGGACCCTGG; TCCCAGGGCACGTCCACCGACAACAATGGGAGACGCTTCACATTATTTTCGGTTTTATTC; GAGCACTTCN;
  3' Read Nucleotide Sequence

  >Forward primer walk for NM_001766 unedited; NTTTTTCTTGGCCCCGATCCTGGCCCTGGCCGTCTGCTGCTGGTGTGCCATGTCTCAGGA; TTCTACCCAAAGCCTGTATGGGTGAAGTGGATGCGGGGTGAGCAGGAGCAGCAGGGCACT; CAGCCAGGGGACATCCTGCCCAATGCTGACGAGACATGGTATCTCCGAGCAACCCTGGAT; GTGGTGGCTGGGGAGGCAGCTGGCCTGTCCTGTCGGGTGAAGCACAGCAGTCTAGAGGGC; CAGGACATCGTCCTCTACTGGGGTGGGAGCTACACCTCCATGGGCTTGATTGCCTTGGCA; GTCCTGGCGTGCTTGCTGTTCCTCCTCATTGTGGGCTTTACCTCCCGGTTTAAGAGGCAA; ACTTCCTATCAGGGCGTCCTGTGACTCGCCTTGCCACATCTGTGTCTCTGGAACCCAGGA; CCTCTGGACCTCAGGTTCCCAAGACTTCAGTCCTGGTCTGCTCAGGAATTGAAGATGTAA; GGAATTGAAGATAGGAGAGATACCTTGAAAAAGTAGAGAACAGTCATGAGGCAGCTTTCA; TCACACCCTTTTAACATTTATCTAAAAGAATTTAAATTCTTTTTCAAAAATTACACTACA; AGTTTATAAGCCCAAATGGCTCTGTGAAATCAGAAGTGCAAAGGTGTGCAAACTTGTATC; TGAAGACCTACCAGGGACAAGCAGGTAAGAGCTGATGTGAGTGTGTGTGATGGGATCTGT; AAGGAACTGNGACACACATGTCCTATCCAAAGGAATCAGCTGCAGCTGCTTGTTGTCAAG; TATAAAGTCAGGACCTGGCTTGGGCTTNACCGTTTTTCAAGAAACTGGAAATCTGGATTT; TCAGCGAACATGCCCTGATTTAAAAGGNTGACTCAGTTTTTACAAATACTATGTGNGACA; CCTCANATACTACCTACTGC;
• Restriction Sites: Please inquire
• ACCN: NM_001766
• Insert Size: 2500 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution Method: 1. Centrifuge at 5,000xg for 5min.; 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.; 3. Close the tube and incubate for 10 minutes at room temperature.; 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.; 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
• Note: Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001766.3, NP_001757.1
• RefSeq Size: 3795 bp
• RefSeq ORF: 1008 bp
• Locus ID: 912
• UniProt ID: P15813
• Cytogenetics: 1q23.1
• Domains: IGc1
• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Hematopoietic cell lineage
• Summary: This gene encodes a divergent member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes to late endosomes and lysosomes via a tyrosine-based motif in the cytoplasmic tail. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2016]; Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).